Status: Recruiting
Small Extracellular Vesicles and Insulin Action
The goals of this research study are to: 1) understand why some people with obesity are protected from developing conditions such as type 2 diabetes and cardiovascular disease while others are more likely to develop obesity-related conditions; 2) assess the effect of small extracellular vesicles (sEVs also called exosomes), obtained from human participants, on metabolic function in cultured cells and in mice.
Participants needed: 72
Trial details
Age: 25-55Biological sex: AllType: InterventionalSponsor: Washington University School of MedicineUpdated: Jul 17, 2025Locations: 1
Eligibility criteria
Metabolically healthy lean subjects must have a BMI ≥18.5 and ≤24.9 kg/m²; Subje... [+2]
History of diabetes, liver disease other than NAFLD or other serious diseases, [+3]