Obessive-Compulsive Disorder

1

Review clinical trials related to Obessive-Compulsive Disorder. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Efficacy and Influencing Factors of Mindfulness-Based Exposure Group Therapy for OCD

Obessive-Compulsive Disorder (OCD) is frequently treatment-refractory and imposes a substantial burden on affected individuals. Although Exposure and Response Prevention (ERP) is widely regarded as the first-line intervention, its inherently distressing nature contributes to treatment refusal and premature dropout in a subset of patients. The present study aims to develop and validate a novel intervention, Mindfulness-Based Exposure Therapy (MBET). In contrast to existing protocols that incorporate mindfulness as an adjunct to ERP and have yielded mixed or limited benefits, this study seeks a theoretically grounded integration of mindfulness and exposure-based principles. We hypothesize that mindfulness training improves emotion regulation, thereby producing a synergistic effect that enhances patients' capacity to engage in and complete exposure tasks. From a clinical perspective, MBET is intended to offer a more tolerable and acceptable alternative to standard ERP, with the potential to improve treatment adherence and clinical outcomes among patients who experience traditional exposure procedures as excessively distressing.

Participants needed: 64
Trial details
Age: 16-55Biological sex: AllType: InterventionalSponsor: Shanghai Mental Health CenterUpdated: Mar 20, 2026Locations: 1
Eligibility criteria

Have a primary diagnosis of Obsessive-Compulsive Disorder (OCD) according to DSM... [+6]

Meet DSM-5 criteria for any other psychiatric disorder besides OCD [+5]