Obstetric Labor Complications

8

Review clinical trials related to Obstetric Labor Complications. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Postnatal Debriefing After Adverse Obstetric Events

Adverse or unexpected obstetric events can negatively affect women's psychological well-being and childbirth experience, increasing the risk of postpartum traumatic stress. However, structured postnatal debriefing is not routinely implemented in clinical practice, and evidence regarding its effectiveness remains limited. This study aims to evaluate the effect of a structured postnatal debriefing conducted within the first 24 hours after childbirth in women who have experienced an adverse or unexpected obstetric event. This quasi-experimental pretest-posttest study will include two consecutive groups: a control group receiving usual postpartum care during the pre-implementation phase and an intervention group receiving structured postnatal debriefing during the implementation phase. The primary outcome is childbirth-related trauma at 6 weeks postpartum. Secondary outcomes include birth satisfaction, early post-traumatic stress symptoms, satisfaction with information and emotional support received after childbirth, and clinical maternal and neonatal outcomes. This study will provide evidence on whether structured postnatal debriefing improves psychological outcomes and contributes to more patient-centered obstetric care.

Participants needed: 142
Trial details
Age: 18+Biological sex: FemaleType: InterventionalSponsor: Parc de Salut MarUpdated: Jun 25, 2026
Eligibility criteria

Women aged 18 years or older. [+5]

Inability to communicate verbally. [+4]

Status: Recruiting

The Periviable GOALS Decision Support Tool

The Periviable GOALS (Getting Optimal Alignment around Life Support) decision support tool (DST) is meant to facilitate informed shared decision-making regarding neonatal resuscitation for families facing the threat of a periviable delivery (deliveries occurring between 22 0/7 - 25 6/7 weeks gestational age). It is designed for parents to review independent of their clinician, and is intended to supplement, not replace, clinician counseling. The focus of the DST is the provision of patient-centered outcomes information and assistance with values clarification regarding neonatal outcomes. This is a multisite, randomized controlled trial to test the effect of the Periviable GOALS DST on shared decision making and decision satisfaction. The investigators hypothesize that participants who utilize the GOALS DST will have improved shared decision making and higher decision satisfaction.

Participants needed: 300
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Indiana UniversityUpdated: May 11, 2026Locations: 12
Eligibility criteria

Adults (18 years or older) [+7]

Under 18 years of age [+7]

Status: Recruiting

MRI Pseudo-CT Sequences for Obstetrical Pelvimetry.

It is possible to perform a pelvimetry by MRI as a substitute to pelvimetry by CT, hence sparing the patient from a dose of irradiation.

Participants needed: 95
Trial details
Age: 18-99Biological sex: FemaleType: InterventionalSponsor: Cliniques universitaires Saint-Luc- Université Catholique de LouvainUpdated: Apr 29, 2026Locations: 1
Eligibility criteria

Pregnant woman 33 to 41 week [+3]

Usual contraindications to MRI (Pacemaker, Metallic foreign body, Cochlear impla... [+2]

Status: Recruiting

Monoferric for Prenatal Iron Deficiency

A prospective observational study of pregnant women with iron deficiency anemia and oral iron intolerance or advanced gestational age.

Participants needed: 80
Trial details
Phase: Early Phase 1Age: 18-65Biological sex: FemaleType: InterventionalSponsor: Oregon Health and Science UniversityUpdated: Sep 19, 2024Locations: 1
Eligibility criteria

Participants 18 years of age or older between 14 to 42 weeks gestation who are d... [+3]

Known infectious, inflammatory, or malignant conditions that may confound iron r... [+1]

Status: Recruiting

Effect of Intravenous Vitamin C on Intrapartum Maternal Fever After Epidural Labor Analgesia

This study aims to explore the effect of intravenous vitamin C infusion on intrapartum fever after epidural labor analgesia, to reduce the impact of intrapartum fever on maternal and infant, improve maternal and infant outcomes, and provide a reference for clinical preventive medication.

Participants needed: 400
Trial details
Phase: Phase 4Age: 18-35Biological sex: FemaleType: InterventionalSponsor: Kunyue LiUpdated: Jul 3, 2024Locations: 1
Eligibility criteria

single-fetus, head position, and full-term vaginal delivery receiving epidural l...

have a fever before epidural analgesia, acute infection on admission, incomplete...

Status: Recruiting

Doppler Findings in the Fetal Cerebral Blood Vessels (VA/MCA) Within 24 Hours Before Delivery and Relation With Perinatal Outcome.

1. Assess differences in flow patterns in the fetal cerebral blood vessels within 24 hours before delivery between fetuses with a normal vs. adverse perinatal outcome. 2. Explore maternal and/or fetal characteristics that might influence technical feasibility of doppler sonography of the fetal cerebral blood vessels in early labor at term. 3. Assess reliability of the technique by measuring intra- and inter-observer variation in a subset of participants.

Participants needed: 120
Trial details
Age: 18+Biological sex: FemaleType: ObservationalSponsor: Universitaire Ziekenhuizen KU LeuvenUpdated: Jul 1, 2024Locations: 1
Eligibility criteria

Singleton pregnancy. [+9]

Advanced labor (> 4cm of cervical dilatation) at the time of admission on the la... [+4]

Status: Recruiting

Prelabor Visual Biofeedback by a Self-operated Ultrasound Device

A substantial number of women report fear of childbirth and negative birth experiences. The objective of the study is to assess the efficacy of visual biofeedback before labor using a self-operated home ultrasound for maternal pushing training, which is expected to reduce fear of childbirth, increase perceived control during birth, prevent prolonged labor and the ensuing maternal and neonatal negative adverse outcomes, and prevent maternal post-traumatic stress symptoms. Intrapartum visual biofeedback provided by obstetricians during the second stage of labor has been shown to increase pushing efficiency and improve maternal obstetric and psychological outcomes. Previously, visual biofeedback has been implemented only in an in-hospital setting and, with one known exception, only during labor. A Mobile Self-Operated Home Ultrasound System has been reported as a feasible and reliable tool for obstetrical ultrasound. A randomized controlled trial will be conducted with three study groups of pregnant women (37-39 weeks of gestation): (1) Obstetrical ultrasound+visual biofeedback in-hospital and at home using self-operated ultrasound; (2) Obstetrical ultrasound+visual biofeedback in-hospital; (3) Obstetrical ultrasound only. Visual biofeedback by ultrasound will be performed by transperineal ultrasound, enabling the future mother to visualize the descent of the fetal head within the birth canal in response to her pushing effort. Follow-up will be conducted two weeks later and at six weeks postpartum. Positive results following the application of biofeedback by self-operated home ultrasound may change the paradigm for pre-labour sonographic education. Self-operated home ultrasound will also enable more comprehensive pre-labor ultrasound-based education and hopefully reduce adverse physical and psychological outcomes following childbirth.

Participants needed: 261
Trial details
Age: 18+Biological sex: FemaleType: InterventionalSponsor: Rabin Medical CenterUpdated: May 6, 2024Locations: 1
Eligibility criteria

Nuliparity [+4]

Multifetal gestation [+2]

Status: Recruiting

Shenzhen Birth Cohort Study

The Shenzhen Birth Cohort Study was set up to investigate the effect of early life environmental exposures on short- and long-term health consequences in Shenzhen, China.

Participants needed: 10,000
Trial details
Age: 15-49Biological sex: AllType: ObservationalSponsor: Sun Yat-sen UniversityUpdated: Feb 5, 2019Locations: 1
Eligibility criteria

1. Pregnant women plan to delivery and participate in child care in our hospital...

Pregnant women who have been pregnant for more than 20 weeks; refuse to particip...