Occlusion

8

Review clinical trials related to Occlusion. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Diagnostic Performance of the Resistance Index (RI) for the Assessment of Cerebral Vasoreactivity in Transcranial Doppler

Routine revascularization of asymptomatic carotid stenosis is questionable as optimal medical therapy has significantly reduced the risk of stroke. Therefore, it is crucial to identify high-risk patients who may still benefit from carotid revascularization. In 2017, the ESC guidelines clarified the criteria associated with a high risk of stroke despite optimal treatment to consider a revascularization procedure, including altered cerebral vasoreactivity. However, cerebral vasoreactivity using transcranial Doppler ultrasound is reserved for qualified centers. It requires a technical platform and trained personnel, is time-consuming and generally not readily available. A simpler test is therefore necessary. The goal is to quickly and easily detect patients with normal vasoreactivity who do not benefit from the cerebral vasoreactivity test (reference standard) and to reserve the time-consuming cerebral vasoreactivity test for patients likely to have altered vasoreactivity. The hypothesis of the study is that on a routine measure in transcranial echo-Doppler, the resistance index (RI), can predict the response to the cerebral vasoreactivity test. With this new test, it will be possible to select patients who do not benefit from pharmacological cerebral vasoreactivity testing ("true negatives"). Thus, the time-consuming cerebral vasoreactivity test will be reserved only for patients with a possibility of impaired vasoreactivity.

Participants needed: 77
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Centre Hospitalier Universitaire de NīmesUpdated: Jun 1, 2026Locations: 1
Eligibility criteria

The patient must have given their free and informed consent and signed the conse... [+6]

The subject is participating in an interventional study, or is in a period of ex... [+14]

Status: Not yet recruiting

Effectiveness of a Needle-free Connector With Anti-reflux Technology in Reducing Complications From Long Peripheral Venous Catheters in Hospitalised Adult Patients: Randomised Clinical Trial

A study to evaluate a needle-free connector (a stopper) featuring anti-reflux technology (to prevent blood from flowing back) for catheters (polyurethane tubes inserted into a vein), with the aim of reducing complications associated with these devices: blockages, infections, pain, etc.

Participants needed: 62
Trial details
Biological sex: AllType: InterventionalSponsor: Hospital Arnau de VilanovaUpdated: Apr 16, 2026
Eligibility criteria

Patients requiring placement of a long peripheral venous catheter. [+2]

Status: Recruiting

Characterization of the Temporo-masseteric Nerve Block (TMNB) in Healthy Subjects

The proposed pilot study is aimed at preliminary characterization of the TMNB injection in 20 healthy volunteers. Assessment of bite-force distribution and surface electromyographic activity of the temporalis and the masseter muscles, at rest and clench, before and after unilateral TMNB injection, will be the primary outcome measures. Post-injection assessments will be performed at 30 minutes, 2 hours, and 2 weeks after the injection. Participants will be surveyed regarding their experience receiving the TMNB injection (secondary outcomes).

Participants needed: 20
Trial details
Phase: Phase 2Age: 18-64Biological sex: AllType: InterventionalSponsor: Rutgers, The State University of New JerseyUpdated: Dec 5, 2025Locations: 1
Eligibility criteria

18-64 years of age [+13]

Traumatic injury/ surgery on face or jaw < 6 months [+11]

Status: Not yet recruiting

Abutment Analysis of Metallic Denture Frameworks in Mandibular Kenedy Class III Cases

This study is aimed to compare CAD/CAM (digitally fabricated) metallic partial denture frameworks to conventionally fabricated metallic partial denture frameworks in mandibular Kennedy class-III arches in terms of abutment health and occlusal analysis

Participants needed: 22
Trial details
Biological sex: AllType: InterventionalSponsor: Cairo UniversityUpdated: Oct 10, 2025
Eligibility criteria

Patients with unilateral bounded saddles in the mandible (Kennedy class III). [+3]

Periodontal affection of the abutment teeth. [+6]

Status: Not yet recruiting

Assessment of the Occlusal Characteristics and Orthodontic Treatment Needs for Egyptian Children( 6-12)Years Old

The objective of this study is to assess the occlusal characteristics of Egyptian children 6-12 years old and their need for orthodontic treatment.

Participants needed: 70
Trial details
Age: 6-12Biological sex: AllType: ObservationalSponsor: Salma Hassan Widatalla OmarUpdated: Feb 18, 2025
Eligibility criteria

Egyptian children of both genders born to Egyptian parents . [+2]

Craniofacial anomalies that affect jaw relation and dentition except for cleft l... [+3]

Status: Not yet recruiting

Evaluation of the Impact of Integrating Dynamic Patient-Specific Motion and Implementing a Jaw Tracking System in the Attribution of the Occlusion in Full-Arch Restorations Through a Digital Workflow: A Clinical Study

The maxillomandibular relationship of diagnostic and definitive casts is a fundamental procedure in prosthodontics. Depending on the prosthodontic treatment involvement, different maxillomandibular relationship records can be selected, including maximal intercuspal position (MIP), centric relation (CR) or most comfortable position. Intraoral scanners (IOSs) provide a digital alternative to obtain diagnostic and definitive casts, as well as the maxillomandibular relationship, by acquiring virtual occlusal records.4 Various techniques are available for tracking and recording the mandibular motion of the patient, including mechanical, photographic, radiographic, electromagnetic, ultrasonic-based devices, and optical motion capturing systems. By implementing a digital jaw tracker, patient's individualized mandibular movement can be recorded and combined with intraoral patient's scan, in order to be simulated through the cad software. However, the accuracy of the maxillomandibular relationship has been evaluated only by one study and for one patient. Also, the accuracy to record and replicate of occlusal contacts, acquired by using optical jaw tracking systems has not been evaluated clinically yet. The purpose of the present study was to clinically evaluate the impact of integrating dynamic patient specific-motion and registration, utilizing a digital jaw analyzer (ModJaw), in the attribution of the occlusion.

Participants needed: 40
Trial details
Age: 18+Biological sex: MaleType: ObservationalSponsor: National and Kapodistrian University of AthensUpdated: Jan 14, 2025Locations: 1
Eligibility criteria

Not listed

Status: Recruiting

3D Evaluation of the Lip Support in a Full-arch Implant-supported Rehabilitations

The goal of this observational study is to evaluate the impact of a full arch implant-supported prostheses in the lip support. In a complex rehabilitation cases, the process between the diagnosis and the delivery of a prostheses may lead with many clinical and laboratorial choices which influence the final design of the prosthetic work and consequently the facial profile of the patient. The use of 3D facial scanners and advanced superimposition methodology allows the investigators to objectively measure several relevant parameters such as vertical occlusion of dimension and lip support.

Participants needed: 20
Trial details
Biological sex: AllType: ObservationalSponsor: Implantology InstituteUpdated: Jun 26, 2024Locations: 1Duration: 1 Year
Eligibility criteria

Individuals with at least a full-arch implant supported rehabilitation in the up... [+3]

Individuals with history of hypersensitivity to external light or any similar co... [+4]

Status: Recruiting

Tunneled Peripherally Inserted Central Catheter (PICC) in Adult Patients and Associated Outcomes

The aim of this multicenter randomized clinical trial is to compare the tunneling technique of PICC insertion with the non-tunneled insertion technique in the incidence of the combined or isolated outcome of catheter-related bloodstream primary infection, thrombosis, obstruction, and accidental dislodgement in the adult population within a period of up to 30 days.

Participants needed: 840
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Hospital de Clinicas de Porto AlegreUpdated: May 20, 2024Locations: 1
Eligibility criteria

adult patients (>= 18 years old) admitted to medical clinics, surgical clinics,...

patients with Chronic Kidney Disease, whether dialytic or not; [+2]