Olverembatinib

2

Review clinical trials related to Olverembatinib. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Phase II Study of the Combination of Subcutaneous Blinatumomab and Olverembatinib in Patients With Philadelphia Chromosome (ph)-Positive and/or BCR::ABL1 Positive Acute Lymphoblastic Leukemia (ALL)

To find out if giving blinatumomab as injections under the skin and olverembatinib can help to control the disease in patients with Ph-positive ALL.

Participants needed: 60
Trial details
Phase: Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: M.D. Anderson Cancer CenterUpdated: May 5, 2026Locations: 1
Eligibility criteria

Performance status ≤2 (ECOG Scale). [+11]

Active serious infection not controlled by oral or IV antibiotics. [+17]

Status: Recruiting

Pharmacokinetics of Olverembatinib in Participants With Hepatic Impairment

This is a non-randomized, open-label, parallel, single-dose study to evaluate the pharmacokinetic profile of olverembatinib in participants with normal or impaired liver function.

Participants needed: 48
Trial details
Phase: Phase 1Age: 18-75Biological sex: AllType: InterventionalSponsor: Ascentage Pharma Group Inc.Updated: Dec 23, 2025Locations: 1
Eligibility criteria

The participant voluntarily joins the study, signs the Informed Consent Form, an... [+3]

Drug-induced liver injury. [+18]