Open Bite

4

Review clinical trials related to Open Bite. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

IOA Preventing Occlusal Changes With MAD Use

This study is evaluating two standard-of-care strategies used to prevent bite changes (occlusal changes) in patients treated with a Mandibular Advancement Device (MAD) for sleep-related breathing disorders such as obstructive sleep apnea (OSA). While MAD therapy is effective, it can lead to changes in how the teeth fit together, including the development of a posterior open bite. Participants in this study will be randomly assigned to one of two standard-of-care approaches: using an interocclusal aligner each morning after removing the MAD, or performing daily jaw exercises. Both methods aim to reduce the risk of occlusal changes. The study will follow participants over a 3-month period and includes dental evaluations, 3D oral scans, and short daily surveys. Findings from this research may help guide best practices for preserving occlusion during MAD therapy.

Participants needed: 30
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Isabel Moreno HayUpdated: May 18, 2026Locations: 1
Eligibility criteria

adult participants (≥18 years) [+2]

pervious orthognathic surgery [+13]

Status: Recruiting

Investigate the Effectiveness of 3D-printed Shape Memory Aligners in the Treatment of Anterior Open Bite

The goal of this randomised clinical trial study is to investigate 3D-printed shape memory aligners in the treatment of anterior dental open bite adult patients. The main questions it aims to answer are: 1. Do 3D-direct-printed shape memory aligners demonstrate potentiality in the management of AOB? 2. What is the effect of 3D-direct printed shape memory aligners on molar intrusion? 3. Can the 3D-direct printed shape memory aligners extrude anterior teeth without the use of attachments? 4. Do 3D-direct printed shape memory aligners generate greater/higher stress distribution and initial teeth displacement compared to conventional clear aligners? Researchers will compare three groups: Group I: Patients treated with conventional clear aligners with attachments; Group II: Patients treated with 3D direct-printed shape-memory aligner without attachment; Group III: Patients treated with 3D direct-printed shape memory clear aligners with attachments and see its effect on anterior open bite treatment. Participants will wear a clear aligner for about 6-8 months. Then

Participants needed: 51
Trial details
Age: 18-35Biological sex: AllType: InterventionalSponsor: Kufa UniversityUpdated: May 11, 2026Locations: 1
Eligibility criteria

Age 18-35 years, [+4]

Patient with a history of trauma to the molars or incisors. [+4]

Status: Recruiting

Stability of Orthodontic Treatment of Anterior Open-bite

The study aims to explore how an open bite malocclusion affects daily life of an individual, is its orthodontic treatment effective, and what kind of burden of care the treatment has caused.

Participants needed: 80
Trial details
Biological sex: AllType: ObservationalSponsor: University of HelsinkiUpdated: May 5, 2026Locations: 1
Eligibility criteria

No malocclusion [+1]

Status: Not yet recruiting

Myofunctional Therapy in Open Bite - RCT

The goal of this clinical trial is to learn if myofunctional therapy in 6-10-year-old children with infant type of swallowing and open bite is effective. Primary hypothesis: myofunctional therapy results in correction of open bite Researchers will compare a group in which myofunctional therapy is performed for 6 months to a group in which myoufunctional therapy will be delayed by 1 year. Participants will exercise according to a pre-established regimen and schedule

Participants needed: 80
Trial details
Age: 6-10Biological sex: AllType: InterventionalSponsor: Piotr FudalejUpdated: Aug 28, 2024
Eligibility criteria

generally healthy children aged 6-10 years, [+3]

finger sucking habit (or similar) occurring within the last 6 months, [+7]