Health Trials

Oral Carcinoma in Situ

2

Review clinical trials related to Oral Carcinoma in Situ. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Rate of Malignant Transformation and Clinical Characteristics Among an Oral Lichen Planus Cohort: a Retrospective Center Experience

The main objective of this paper will be to evaluate the rate of malignant transformation among a cohort of patients affected by oral lichen planus with long-term follow-up. Secondary aims will be to study and describe the characteristics of these patients to identify potential risk factors for malignant transformation, and to evaluate the therapeutic effects and features to OLP drgus.

Participants needed: 300
Trial details
Biological sex: AllType: ObservationalSponsor: Catholic University of the Sacred HeartUpdated: May 14, 2026Locations: 1
Eligibility criteria

Clinical-histological diagnosis of Oral lichen planus [+2]

Patients who did not give consensus to personal data treatment [+3]

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Status: Recruiting

A Proof of Concept Trial Investigating Safety and Efficacy of APG-157 in Oral Dysplasia

The purpose of this study is to assess whether APG-157 can reduce the tumor size in participants with the study disease. Another purpose is to find out about the effects of APG-157 on certain tumor markers and oral rinses in participants with the study disease.

Participants needed: 32
Trial details
Phase: Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: Elizabeth J FranzmannUpdated: Jan 14, 2026Locations: 1
Eligibility criteria

Adult patients age > 18 years with biopsy-proven moderate to severe oral dysplas... [+8]

Pregnant women. [+10]

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