Status: Not yet recruiting
CLASSIFY-OMM: Multicenter Rare Disease Cohort for T-Stage Reclassification and Molecular Subtyping-Based Precision Therapy in Oral Mucosal Melanoma
This bidirectional cohort study (retrospective + prospective) focuses on three key challenges in oral mucosal melanoma (OMM): clinical staging based on depth of invasion (DOI), molecular subtyping, and precision therapy. By integrating DOI-driven T-stage reclassification, genomic profiling, and longitudinal follow-up, we aim to build a population-specific, high-quality evidence resource to support refined staging, CDK4-targeted treatment, and prognostic modeling for Chinese OMM patients.
Participants needed: 1,100
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong UniversityUpdated: Jun 23, 2026Locations: 1
Eligibility criteria
Histopathologically confirmed primary oral mucosal melanoma (WHO criteria);
Primary melanoma originating from skin, eye, esophagus, or other non-oral mucosa...