Osteoarthritis of the Knees

3

Review clinical trials related to Osteoarthritis of the Knees. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Determining the Optimal Dose of AD-211 in Patients With Osteoarthritis of the Knee

The purpose of this study is to determine the optimal dose of AD-211 in patients with osteoarthritis of the knee.

Participants needed: 200
Trial details
Phase: Phase 2Age: 19-75Biological sex: AllType: InterventionalSponsor: Addpharma Inc.Updated: Apr 24, 2026
Eligibility criteria

Signed informed consent [+2]

Patients with secondary osteoarthritis of the knee [+1]

Status: Not yet recruiting

Evaluation of Intra-articular CX-011 to Treat Moderate to Severe Pain From Knee Osteoarthritis

Study is designed to evaluate the safety and effectiveness of a drug called CX-011 to treat pain in patients with osteoarthritis of the knee. Osteoarthritis produces pain in the knee (and other joints) that typically is worsened by activities such as long distance walking and is alleviated by rest.

Participants needed: 72
Trial details
Phase: Phase 1, Phase 2Age: 40-75Biological sex: AllType: InterventionalSponsor: CarthroniX, Inc.Updated: Dec 30, 2025
Eligibility criteria

Written consent to participate in the study. [+12]

Daily use of assistive devices (e.g. cane or walker) or presence of comorbiditie... [+18]

Status: Recruiting

Clinical Study of Acupuncture Treatment of Knee Osteoarthritis

The main question of this study was to evaluate the efficacy and safety of acupuncture in the treatment of knee osteoarthritis (KOA) through a single-blind, randomized controlled trial divided into two groups. Patients in both groups received a total of 24 acupuncture treatments over an 8-week period. The differences in knee NRS score, WOMAC index, walking test, mental health assessment and other indicators between the acupuncture group and the sham acupuncture group before and after treatment were compared to provide high-quality evidence to support the effectiveness of acupuncture in treating KOA.

Participants needed: 350
Trial details
Age: 18-70Biological sex: AllType: InterventionalSponsor: Wu zenanUpdated: Feb 3, 2025Locations: 1
Eligibility criteria

aged 18-70 years old, regardless of gender [+4]

Patients with a history of knee surgery [+6]