Ovarian Function

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Review clinical trials related to Ovarian Function. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Exogenous Progesterone as Ovulation Trigger

The goal of this clinical trial is to learn whether the sudden administration of vaginal micronized progesterone during the late follicular phase can trigger an LH surge and reactivation of oocyte meiosis in healthy oocyte donors aged 18 to 33 undergoing a mild ovarian stimulation cycle. The main question it aims to answer is: * Does progesterone administered in the late follicular phase induce an LH surge and subsequent oocyte meiosis reactivation? Participants will: * Undergo a mild ovarian stimulation with 75 IU of follitropn alfa * Start vaginal micronized progesterone (400 mg every 12 hours) once at least one follicle reaches 15 mm * Have blood samples collected to measure hormone levels before and after progesterone administration * Undergo oocyte retrieval 35-36 hours after the progesterone trigger This is a low-intervention, single-center pilot study including approximately 10 oocyte donors.

Participants needed: 10
Trial details
Phase: Phase 4Age: 18-33Biological sex: FemaleType: InterventionalSponsor: Instituto Valenciano de Infertilidade de LisboaUpdated: Jun 4, 2026Locations: 1
Eligibility criteria

Informed Consent Form dated and signed correctly prior to the performance of any... [+4]

Presence of ovarian cyst(s) detected on the baseline (initial) ultrasound examin... [+6]