Overweight and Obese Volunteers.

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Review clinical trials related to Overweight and Obese Volunteers.. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Evaluate LAE102 in Healthy and Overweight/Obese Subjects

The purpose of this study is to evaluate the safety, tolerability and pharmacokinetics of LAE102 injection in healthy and overweight/obese participants, and also evaluate the preliminary pharmacodynamic effect of multiple dose injections in overweight/obese participants.

Participants needed: 160
Trial details
Phase: Phase 1Age: 18-65Biological sex: AllType: InterventionalSponsor: Laekna LimitedUpdated: Jan 9, 2026Locations: 1
Eligibility criteria

Male or female and aged 18 to 65 years (inclusive) at the screening visit [+6]

With clinically significant abnormalities in vital signs, physical examination,... [+20]

Status: Not yet recruiting

Weight Reduction With the Low-Insulin-Method - Self Monitoring of Breath Acetone

The goal of this clinical trial is to learn if lifestyle intervention with information about ketosis state supports weight reduction in overweight adults. Researchers will compare an App-based lifestyle intervention with self-monitoring of breath acetone vs. lifestyle intervention alone. Participants will: Get a lifestyle intervention via the LIM-App for 12 months. Report body weight.

Participants needed: 42
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: West German Center of Diabetes and HealthUpdated: Jun 29, 2025Locations: 1
Eligibility criteria

Body Mass Index > 25kg/m2

Status: Recruiting

A Phase I/IIa Clinical Study to Assess the Single and Multiple Ascending Doses of MDR-001 Tablets in Healthy Participants and Obese/ Overweight Participants

To investigate the safety and tolerability after single and multiple ascending doses of MDR-001 Tablets administered orally in healthy participants and obese/ overweight participants.

Participants needed: 131
Trial details
Phase: Phase 1, Phase 2Age: 18-55Biological sex: AllType: InterventionalSponsor: MindRank AI LtdUpdated: Mar 7, 2025Locations: 1
Eligibility criteria

Participants who are aged ≥ 18 and ≤ 55 years at the time of signing the informe... [+2]

Participants with any condition that increases the risk of bleeding, such as hem... [+11]