Status: Not yet recruiting
AI-assisted Multi-domain Lifestyle Versus Tirzepatide for Weight Loss Maintenance in Adults With Type 2 Diabetes (AIM-MAINTAIN)
This is a randomized controlled trial to compare the effect of AI-assisted multi-domain lifestyle and continued tirzepatide on body weight loss maintenance. The study consists of two phases: a 20-week lead-in phase, during which all participants will receive weekly subcutaneous tirzepatide at the maximum tolerated dose (MTD), followed by a 52-week intervention phase. Participants who meet the randomization criteria after the lead-in phase will be randomly assigned to either AI-assisted multi-domain lifestyle intervention or tirzepatide 5 mg
Participants needed: 400
Trial details
Phase: Phase 4Age: 18-65Biological sex: AllType: InterventionalSponsor: Huazhong University of Science and TechnologyUpdated: Apr 29, 2026Locations: 1
Eligibility criteria
Male or female participants aged 18 to 65 years at the time of signing informed... [+3]
History of type 1 diabetes mellitus or other types of diabetes, or treatment wit... [+26]