Pain, Back

7

Review clinical trials related to Pain, Back. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Lumbar Steroid Use in Patients Undergoing Posterior Lumbar Decompression

This study seeks to evaluate the impact of intra-operative topical epidural steroid usage in patients undergoing 1-2 level lumbar laminectomy. The study will examine post-operative opioid usage, length of stay, return to work, and patient reported outcomes following these procedures.

Participants needed: 150
Trial details
Phase: Phase 3Age: 18-85Biological sex: AllType: InterventionalSponsor: Hospital for Special Surgery, New YorkUpdated: Apr 28, 2026Locations: 1
Eligibility criteria

Patients scheduled to undergo 1 to 2 level laminectomy [+1]

Minimally invasive surgery [+5]

Status: Recruiting

Regional Nerve Blocks to Improve Analgesia and Recovery in Older Adults Undergoing Spinal Fusion

This initial study is a feasibility study for implementing thoracolumbar interfascial plane, or TLIP, blocks in older adults undergoing spinal fusion. TLIP blocks are done by using anesthesia. In this case, it will be done to either side of the back where surgery will be performed. This has been shown to decrease pain the patients have post-operatively in previous research. In this study, the investigators will examine recruitment rates, completion of assessments, dropout rate, gather patient feedback, and identify barriers to performing TLIP. Further, this feasibility study will provide data to determine adequate sample size and refine methods and outcomes for a future randomized clinical trial. The ultimate goal is to perform a large, appropriately powered randomized control trial to determine the effect of TLIP blocks on pain, physical function and disability, opioid consumption, and delirium in older adult undergoing spinal fusion.

Participants needed: 50
Trial details
Phase: Early Phase 1Age: 65+Biological sex: AllType: InterventionalSponsor: University of IowaUpdated: Mar 27, 2026Locations: 1
Eligibility criteria

Are 65 or older [+5]

64 years old and younger [+15]

Status: Recruiting

Effects of Reformer Pilates in Pregnant Women

Pregnancy is known as a period associated with important physiological and psychological changes in women's lives. There is moderately sufficient evidence in the literature to recommend supplementing prenatal physical activity for maternal health benefits. It has been reported that physical exercise by pregnant women in the absence of obstetric contraindications will not pose a risk to the health of the mother and fetus. In the literature, there are no studies examining the effects of reformer pilates on pain, functional capacity, lumbopelvic stabilization, diastasis recti abdominis, abdominal muscle thickness, respiratory functions, pelvic floor dysfunction, urinary incontinence, sexual function, and venous insufficiency in pregnant women. Therefore, this study aimed to investigate the effects of reformer pilates on pain, functional capacity, lumbopelvic stabilization, diastasis recti abdominis, abdominal muscle thickness, respiratory functions, pelvic floor dysfunction, urinary incontinence, sexual function, and venous insufficiency in pregnant women.

Participants needed: 30
Trial details
Age: 18-35Biological sex: FemaleType: InterventionalSponsor: Izmir Democracy UniversityUpdated: Jan 16, 2025Locations: 1
Eligibility criteria

Single pregnancy [+5]

Multiple pregnancies [+4]

Status: Recruiting

PREventing Pain After Surgery

The present study aims to adapt and modify a brief presurgical Acceptance and Commitment Therapy (ACT) intervention aimed at preventing the transition to Chronic Post-Surgical Pain (CPSP) and reducing long-term opioid use. Investigators will then assess the acceptability, feasibility, and preliminary efficacy of the finalized intervention to prevent the transition to CPSP and reduce post-surgical opioid use six months following lumbar spine surgery. Finally, investigators will identify psychosocial and psychophysical phenotypes associated with response to this intervention.

Participants needed: 140
Trial details
Age: 22+Biological sex: AllType: InterventionalSponsor: Brigham and Women's HospitalUpdated: Oct 28, 2024Locations: 1
Eligibility criteria

scheduled to undergo fusion, discectomy, vertebroplasty, kyphoplasty, or foramin... [+2]

inability to complete study procedures due to delirium, dementia, psychosis, or... [+5]

Status: Not yet recruiting

The Effect of Automatic Massage Applied to Healthcare Workers on Pain, Fatigue and Psychological Well-being

To determine the effect of automatic massage applied to healthcare workers on pain, fatigue and psychological well-being. This research is planned as a pretest-posttest type study. It will be held in the Osmaniye State Hospital maternity ward. The application will be applied by one person in the rest room. Data will be collected using the Introductory Information Form, Psychological Well-Being Scale, Perceived Stress Scale (ASÖ/PSÖ-14), State-Trait Anxiety Inventory (STAI), and Piper Fatigue Scale.

Participants needed: 25
Trial details
Biological sex: AllType: InterventionalSponsor: Emine YıldırımUpdated: Jul 17, 2024
Eligibility criteria

Working in the delivery room

Being receiving psychiatric treatment (Pharmacotherapy or psychotherapy), [+1]

Status: Recruiting

Brown Adipose Tissue Activation by Spinal Cord Stimulation

The objective of this study is to investigate and utilize spinal cord stimulation (SCS) as an effective approach to eliciting weight loss and potentially alleviating Type 2 diabetes mellitus (DM), as evidenced by increasing metabolism of adipose tissue.

Participants needed: 10
Trial details
Age: 21-70Biological sex: AllType: InterventionalSponsor: Oregon Health and Science UniversityUpdated: Apr 3, 2024Locations: 1
Eligibility criteria

Age: 21-70 years [+4]

Not considering SCS for pain [+10]

Status: Recruiting

Trigger Point Injections in Anterior Cervical Surgery

To achieve appropriate exposure for an anterior neck surgery (for example an Anterior Cervical Discectomy and Fusion or ACDF), patients are positioned supine with their neck extended. Due to being in this position, patients frequently complain of posterior neck stiffness and pain postoperatively in addition to the anterior incisional pain. This posterior cervical pain can be classified as myofascial pain. Cervical myofascial pain is thought to be the result of overuse or trauma to the supporting muscles of the neck and shoulders. Trigger point injections are one of the methods used to treat myofascial pain. The trigger point injection procedure is where a physician (typically an anesthesiologist) performs an exam of the patient neck and upper back and finds areas of point tenderness. The physician will then inject a small amount of numbing medication (such as bupivacaine) into the muscle or tissue in that area. Trigger point injections have been shown to be superior to botox injections or dry needling, and equivalent to physical therapy. However, these studies were performed on patients with chronic neck pain. There are no studies evaluating the effectiveness of trigger point injections on post anterior cervical surgery patients. At our institution, trigger point injections with local anesthetic are used as part of a multimodal pain control regimen for post-anterior cervical surgery patients. Our hypothesis is if the addition of trigger point injections to standard of care multi-modal post-operative pain control will decrease patients' myofascial pain, and thereby decrease the amount of narcotic pain medication used.

Participants needed: 60
Trial details
Phase: Phase 4Age: 18+Biological sex: AllType: InterventionalSponsor: George Washington UniversityUpdated: Dec 8, 2022Locations: 1
Eligibility criteria

Elective anterior cervical surgery

Emergency surgery [+3]