Paranoia

3

Review clinical trials related to Paranoia. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Racial Disparities in the Expression of Paranoia

Paranoia is a pattern of thinking in which people feel suspicious or believe others may want to harm them. It can occur in many people, not only those with a mental health diagnosis, and it can affect daily life, relationships, and overall well-being. Research has consistently shown that Black Americans report higher levels of paranoia than White Americans, even when they do not have a clinical diagnosis. However, the reasons for this difference are not well understood. The goal of this study is to better understand why these differences exist. In the experimental part of the study, researchers will use a randomized design to test whether exposure to stressful experiences related to race leads to higher levels of paranoia among Black American participants. The study will also examine factors that may strengthen or weaken this effect, such as individual experiences and personal characteristics. By identifying how stressful experiences related to race influence paranoia, this research aims to improve how paranoia is measured and understood across different groups. These findings may help researchers and clinicians use more accurate and culturally appropriate tools to assess psychosis-related experiences in diverse populations.

Participants needed: 480
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Indiana UniversityUpdated: Apr 29, 2026Locations: 1
Eligibility criteria

18 years of age or older [+4]

Younger than 18 years of age [+4]

Status: Recruiting

Acceptability and Feasibility of a Brief Paranoia Intervention.

The goal of this feasibility and acceptability trial is to test whether a new brief talking therapy can be successfully provided to and is suitable for adolescents (16-18) who are seeking help from Child and Adolescent Mental Health Services (CAMHS). The main research question for the current study is: Is it feasible and acceptable to offer a brief values-based (helping young people identify what matters most to them) and imagery (using imagination to visualise positive experiences) intervention for adolescents experiencing paranoia in CAMHS? It also aims to identify preliminary clinical outcomes, particularly changes in paranoia severity as measured by the Revised Green et al., Paranoid Thoughts Scale (R-GPTS). Participants will complete an eligibility assessment and those eligible will be offered a six-session intervention. Assessment measures will be completed before, during and after the intervention.

Participants needed: 8
Trial details
Age: 16-18Biological sex: AllType: InterventionalSponsor: Lucy JonasUpdated: Jan 20, 2026Locations: 1
Eligibility criteria

Aged 16-18 [+6]

Severe comorbid diagnoses apparent at the initial assessment (e.g., a primary al... [+3]

Status: Recruiting

Supporting Patients by Family Education in Psychotic Illness: A Prospective Cohort Study

Background: A lack of education, resources, and support for family carers of young adults with psychotic illnesses leaves them ill-equipped to support their loved one. Although family support groups exist, few groups offer evidence-based, skills-focused, psychoeducation taught by certified professionals and provided on a public-health level. By equipping families with skills and knowledge, public healthcare harnesses a powerful ally to maintain community stabilization. Aims: The primary study goal is to implement a psychoeducation intervention for family carers supporting young adults with psychosis to reduce family burden and foster community stabilization of service users. Methods: A longitudinal pre-post design will be used to assess the long-term effectiveness of the psychoeducation intervention for family carers supporting a young adult with psychosis on service utilization and functional indexes. Nine expert-reviewed, and family peer-informed psychoeducation modules are administered in 2-hour sessions over 9 weeks to family carers. Conclusion: Presenting the novel approach of an expert-reviewed, peer-informed psychoeducation intervention for family carers, with a focus on knowledge and skill development, the researchers contribute to literature and best practice in patient and family-centered care.

Participants needed: 113
Trial details
Age: 17-27Biological sex: AllType: InterventionalSponsor: University of AlbertaUpdated: Nov 18, 2025Locations: 4
Eligibility criteria

Young adult service user is aged 17-27 at time of recruitment [+1]

Not proficient in English [+1]