Pediatric Respiratory Distress Syndrome

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Review clinical trials related to Pediatric Respiratory Distress Syndrome. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Closed-loop Synchronization Versus Conventional Synchronization

A prior research indicated that asynchrony between the patient and ventilator occurred in 33 percent of 19,175 breaths, and was seen in every patient. The most prevalent kind of asynchrony was ineffective triggering (68%), followed by delayed termination (19%), double triggering (4%) and premature termination (3%). Asynchrony between the patient and ventilator increased considerably with decreasing levels of peak inspiratory pressure, positive end-expiratory pressure, and set frequency.Despite this, more asynchrony categories exist, and there is no widely accepted categorization. Major asynchronies, however, include auto trigger, ineffective effort, and double trigger, while minor asynchronies include early/late cycle, trigger delay, and spontaneous breaths during a mandatory breath. This study aims to compare the safety and efficacy of a closed-loop synchronization controller with conventional control of synchronization during invasive mechanical ventilation of spontaneous breathing of pediatric patients in a pediatric intensive care unit (PICU).

Participants needed: 15
Trial details
Age: 1-18Biological sex: AllType: InterventionalSponsor: Dr. Behcet Uz Children's HospitalUpdated: Mar 19, 2025Locations: 5
Eligibility criteria

Pediatric patients older than 1 month and younger than18 years of age [+2]

Formalized ethical decision to withhold or withdraw life support [+6]