Pediatric Sepsis-induced Multiple Organ Dysfunction Syndrome (MODS)

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Review clinical trials related to Pediatric Sepsis-induced Multiple Organ Dysfunction Syndrome (MODS). Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Targeted Reversal of Inflammation in Pediatric Sepsis-induced MODS

The TRIPS study is a prospective, multi-center, double-blind, adaptively randomized, placebo-controlled clinical trial of the drug anakinra for reversal of moderate to severe hyperinflammation in children with sepsis-induced multiple organ dysfunction syndrome (MODS).

Participants needed: 500
Trial details
Phase: Phase 2, Phase 3Age: 1-17Biological sex: AllType: InterventionalSponsor: Nationwide Children's HospitalUpdated: Mar 13, 2026Locations: 32
Eligibility criteria

≥ 40 weeks corrected gestational age to < 18 years; AND [+3]

Weight <3kg; OR [+11]