Peridontal Disease

3

Review clinical trials related to Peridontal Disease. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Efficacy of Resveratrol Containing Mouthwash in Reducing Halitosis Related Porphyrymonas Gingivalis.

The aim of the study: To assess the efficacy of antioxidant (resveratrol) mouthwash in reducing the level of p. gingivitis and oral malodor over 7 day period among undergraduate dental student patients from Mustansiriyah University/College of Dentistry and Wasit University /College of Dentistry. Objectives: * To assess the efficacy of anti-oxidant and anti-inflammatory resveratrol mouthwash in reducing halitosis in undergraduate students with plaque-induced gingivitis patients. * To assess the efficacy of resveratrol mouthwash in reducing p. gingivalis in undergraduate students' patients with oral malodor. * To determine the relation between p.gingivalis and clinical periodontal parameters (plaque index, gingival index, bleeding on probing) among undergraduate students with plaque-induced gingivitis and halitosis.

Participants needed: 54
Trial details
Phase: Phase 3Age: 20-24Biological sex: AllType: InterventionalSponsor: Al-Mustansiriyah UniversityUpdated: Mar 18, 2025Locations: 1
Eligibility criteria

Organoleptic tongue of scores > 2 using (0-5scale) (Rosenberg and McCulloch, 199... [+7]

Smokers and alcoholics [+9]

Status: Recruiting

The Effect of Hypnosis on Periodontal Treatment

Treatment of periodontal diseases relies on the mechanical removal of microbial dental plaque, calculus, and necrotic cementum from root surfaces in both supra- and subgingival areas to control inflammation in periodontal tissues. As in all dental treatments, dental phobia and dental anxiety are common challenges in initial periodontal therapy. Hypnosis is among the traditional non-pharmacological behavior management techniques used to manage stress and improve pain tolerance. It is known that hypnosis is effective in anxiety control in dentistry. The use of salivary levels of inflammatory mediators released during the disease is a valid method for assessing the progression of periodontal disease and healing after treatment. In this study, the effect of hypnosis on healing in patients undergoing Phase I periodontal therapy will be evaluated by comparing the mean differences in cytokine levels between case and control groups

Participants needed: 50
Trial details
Age: 20-65Biological sex: AllType: InterventionalSponsor: Afyonkarahisar Health Sciences UniversityUpdated: Feb 5, 2025Locations: 1
Eligibility criteria

Not listed

Status: Recruiting

Assessment of Pro-Resolution Mediator Levels in Periodontitis Stage III and IV Before and After Periodontal Therapy

This study aims to assess Pro-Resolution Mediator levels during non-surgical periodontal therapy in individuals with Stage III and IV periodontitis, comparing them to healthy subjects. Periodontitis, a chronic inflammatory condition affecting tooth-supporting tissues, can lead to tooth loss and systemic complications. Understanding the role of pro-resolving lipid mediators in inflammation resolution may offer insights into therapeutic benefits associated with these mediators.

Participants needed: 22
Trial details
Age: 18-80Biological sex: AllType: InterventionalSponsor: Cairo UniversityUpdated: Jan 23, 2025Locations: 2
Eligibility criteria

Adult patients above 18 years old. [+7]

1. Pregnancy or lactation. 2. Smoking more than 20 cigarettes. 3. Immuno-inflamm... [+5]