Health Trials

Persistant Atrial Fibrillation

4

Review clinical trials related to Persistant Atrial Fibrillation. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

A Global Study Comparing Pulsed Field Ablation With Electrographic Flow Mapping Versus Posterior Wall Ablation for Persistent Atrial Fibrillation

The purpose of this study is to establish the safety of the pulsed field ablation (PFA) therapy of Pulmonary Veins and Electrographic Flow (EGF) identified extra-PV sources of atrial fibrillation (PVI + EGF ablation of sources) and to demonstrate its non-inferiority in effectiveness compared to PFA of Pulmonary Veins and LA Posterior Wall (PVI+ PWA) in the treatment of de novo symptomatic drug-refractory persistent atrial fibrillation (PersAF).

Participants needed: 699
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Boston Scientific CorporationUpdated: Jun 30, 2026Locations: 42
Eligibility criteria

≥ 18 years of age, or older if required by local law [+6]

Left atrial anteroposterior diameter ≥ 5.5 cm, or if1 LA diameter not available,... [+54]

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Status: Recruiting

Coherent Sine Burst Electroporation (CSE) Ablation System US IDE Study for Patients With Atrial Fibrillation

To evaluate the safety and effectiveness of the Argá Medtech CSE Ablation System in the treatment of atrial fibrillation.

Participants needed: 360
Trial details
Age: 18-80Biological sex: AllType: InterventionalSponsor: Arga Medtech SAUpdated: Jun 5, 2026Locations: 27
Eligibility criteria

Patients between the ages of 18 and 80 years, or older than 18 if required by lo... [+4]

In the opinion of the Investigator, any known contraindication to an AF ablation... [+27]

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Status: Not yet recruiting

The Effect of Pulse Field Ablation of Atrial Fibrillation Involving Posterior Wall Ablation on Atrial Mechancis Assessed by Cardiac Magnetic Resonance Imaging

Assessing the impact of a new atrial fibrillation (AF) catheter ablation energy on left atrial structure and function is of crucial importance. The goal of this clinical trial is to assess the effect of pulsed-field ablation of atrial fibrillation on left atrial structure.

Participants needed: 39
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Assistance Publique - Hôpitaux de ParisUpdated: Mar 30, 2026
Eligibility criteria

Patient age ≥ 18 [+6]

Only pulmonary vein isolation is scheduled [+11]

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Status: Recruiting

Ablation With the PFA System With a Large-Area Focal Catheter for the Treatment of Persistent Atrial Fibrillation

The study evaluates the safety and effectiveness of the investigational QuickShot Nav configuration of the CardioWave System for focal catheter ablation of persistent atrial fibrillation (PerAF).

Participants needed: 200
Trial details
Age: 18-75Biological sex: AllType: InterventionalSponsor: CardioFocusUpdated: Dec 15, 2025Locations: 3
Eligibility criteria

Physician's note indicating symptoms consistent with recurrent symptomatic PAF A... [+9]

Long-standing persistent AF (continuous AF sustained > 1 year) [+45]

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