Persistent Spinal Pain Syndrome Type 2 (PSPS-T) Lower Spine

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Review clinical trials related to Persistent Spinal Pain Syndrome Type 2 (PSPS-T) Lower Spine. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Evaluation of Medication Tapering on the Sensitivity of the Spinal Cord Using Closed-Loop Spinal Cord Stimulation (Pilot Study)

This pilot study investigates the effects of reducing pain medication including opioids and anticonvulsants, on spinal cord sensitivity during closed-loop spinal cord stimulation (SCS). Patients with Persistent Spinal Pain Syndrome Type 2 (FBSS/FNSS) will undergo a standard 21-day SCS trial with the Evoke closed-loop system, followed by permanent implantation if successful. Neurophysiological responses (activation plots, conduction velocity, chronaxie, rheobase) and patient-reported outcomes (VAS, activity, sleep, medication intake) will be collected during the trial and up to 6 months after implantation. The goal is to evaluate the relationship between medication tapering and spinal cord sensitivity

Participants needed: 20
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Brai²nUpdated: Mar 31, 2026Locations: 1Duration: 6 Months
Eligibility criteria

Candidate for SCS and scheduled for trial with Evoke system. [+9]

Active disruptive psychiatric disorder or condition impacting pain perception or... [+5]