Status: Recruiting

A Pilot Study to Correlate 4-18F- Fluoro-1-naphthol 18F-4FN PET/CT Imaging With Chronic Graft Versus Host Disease Manifestations

To study the safety and possible side effects of using the imaging agent 4-\[18F\]Fluoro-1-Naphthol (also called \[18F\]4FN) in PET/CT scans for participants with chronic GVHD.

Participants needed: 16

Trial details

Phase: Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: M.D. Anderson Cancer CenterUpdated: Jun 10, 2026Locations: 1

Eligibility criteria

Chronic GVHD involving the joints, defined as any limitation of range of motion... [+14]

Unable to comply with all study procedures (for example, participants who are un... [+5]

Status: Recruiting

Study on c-Met Targeted PET/CT Imaging in NSCLC

The investigators developed a 18F labeled small molecule, 18F-TSPF, based on c-Met TKI, as a targeted molecular imaging agent for noninvasive and repeatable detecting c-Met activation status.

Participants needed: 88

Trial details

Age: 18-75Biological sex: AllType: InterventionalSponsor: Xilin SunUpdated: Apr 4, 2025Locations: 1

Eligibility criteria

Age range 18-75 years, open to both male and female participants; [+7]

Severe abnormalities in liver and renal function and blood counts; [+6]

Status: Recruiting

68Ga-RM26-RGD PET/CT Imaging in the GRPR and αvβ3 Positive Tumor Patients

Based on the high expression of specific receptors on the surface of diseased tissues and neovascularization, noninvasive targeted molecular imaging can be used to visualize lesions in vitro by combining specific ligands labeled with short half-life isotopes. In this study, a novel dual-target imaging agent 68Ga-RM26-RGD was used for clinical study of tumor PET/CT imaging to further verify its clinical application value.

Participants needed: 90

Trial details

Phase: Early Phase 1Age: 18+Biological sex: AllType: InterventionalSponsor: Peking Union Medical College HospitalUpdated: Jul 5, 2024Locations: 1

Eligibility criteria

patients with confirmed or suspected breast/brain/prostate cancer; [+2]

pregnancy; [+2]