Pilonidal Cyst

2

Review clinical trials related to Pilonidal Cyst. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Topical Anti-Androgens in Pilonidal Sinus Disease

The goal of this randomized clinical trial is to test the topical drug clascoterone in patients with pilonidal disease, which is a common, benign skin condition of the gluteal cleft. The main questions it aims to answer are: * Does clascoterone improve the severity of pilonidal disease as scored by a physician? * Does clascoterone improve patient symptoms due to pilonidal disease? * Does clascoterone improve the inflammation seen under the microscope in pilonidal disease removed at surgery Participants will apply clascoterone or a placebo cream to the diseased area for 3 months. They will be assessed every 4 weeks for disease severity assessed by a physician viewing patient photos and a symptom-based survey. Researchers will compare participants who received clascoterone treatment to those who received placebo.

Participants needed: 75
Trial details
Phase: Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: University of PennsylvaniaUpdated: Feb 27, 2026Locations: 1
Eligibility criteria

Age 18 and above [+3]

Current use of any topical medication to natal cleft [+5]

Status: Recruiting

Evaluation of the Impact of Pilonidal Cyst Recurrence on Quality of Life in Patients Previously Treated With Conventional Surgery or Laser Therapy

The goal of this observational study is to describe the impact of recurrence on the quality of life of patients treated with radical surgery and laser therapy. The secondary objective is to describe in patients treated with radical surgery and laser treatment : * Intensity of pain and discomfort * Duration of nursing care since surgery * Duration of inactivity since intervention

Participants needed: 100
Trial details
Age: 14+Biological sex: AllType: ObservationalSponsor: GCS Ramsay Santé pour l'Enseignement et la RechercheUpdated: Sep 26, 2025Locations: 1
Eligibility criteria

Patient aged 14 or over [+5]

Symptoms less than 6 months old [+7]