Platinum Resistant High Grade Serous Ovarian Cancer

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Review clinical trials related to Platinum Resistant High Grade Serous Ovarian Cancer. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Paclitaxel Lipid Suspension for Patients with Platinum-Resistant /Refractory Ovarian Cancer

This is a phase-3, open-label, multicenter, two-arm treatment study to evaluate the efficacy and safety of weekly Paclitaxel Lipid Suspension compared with weekly conventional paclitaxel in participants with platinum-resistant/refractory recurrent high-grade serous epithelial ovarian cancer. Paclitaxel Lipid Suspension or conventional paclitaxel will be administered intravenously at a dose level of 80 mg/m2 on Day 1, Day 8 and Day 15 of each 28 days cycle. The primary objective is to establish the non-inferiority of Paclitaxel Lipid Suspension in comparison with conventional paclitaxel for Injection in participants with platinum-resistant/refractory recurrent advanced high-grade serous epithelial ovarian cancer including fallopian tube and/or primary peritoneal cancer. Participants in both arms will be dosed with the drug until disease progression as assessed by investigator and/or unacceptable toxicity.

Participants needed: 166
Trial details
Phase: Phase 3Age: 18+Biological sex: FemaleType: InterventionalSponsor: Jina Pharmaceuticals Inc.Updated: Mar 10, 2025
Eligibility criteria

The participant is willing to give written signed and dated informed consent to... [+18]

Have previously received paclitaxel at any time in the platinum-resistant settin... [+21]