Portal Shunt Systemic

1

Review clinical trials related to Portal Shunt Systemic. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Endoscopic Shunts Embolization for Refractory Hepatic Encephalopathy

The goal of this clinical trial is to learn if endoscopic ultrasound guided (EUS guided) spontaneous porto-systemic shunt (SPSS) embolization works to treat refractory hepatic encephalopathy in adults. It will also learn about the safety of EUS guided embolization. The main questions it aims to answer are: 1. Does EUS guided embolization maintain an acceptable safety profile? 2. Does EUS guided embolization of large SPSS result in significant clinical improvement in patients with refractory hepatic encephalopathy? Participants will: 1. Receive EUS guided embolization or medical management. 2. Receive follow-up EUS procedures one month after embolization for assessment of the shunt patency and development of varices (embolization group). 3. Receive follow-up every week for 4 weeks to assess degree of worst episode of hepatic encephalopathy via West Haven criteria.

Participants needed: 34
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Rutgers, The State University of New JerseyUpdated: Apr 28, 2026Locations: 1
Eligibility criteria

Adults aged ≥18 years with known cirrhosis [+3]

Severe/refractory ascites defined as ascites that does not recede after medical... [+5]