Positive C. Acnes Culture

1

Review clinical trials related to Positive C. Acnes Culture. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Post-incision Antimicrobial Wash vs C. Acnes in Shoulder Arthroplasty

The purpose of this randomized controlled trial is to determine the effect of post-incision wash using various novel antimicrobial solutions on the rate of positive C. Acnes cultures collected from adults undergoing primary shoulder replacement surgery. Subjects will be randomly assigned in a 1:1:1:1 fashion to groups that will receive one of the following treatments: * Post-incision application of Xperience Antimicrobial wash (NextScience, Jacksonville, FL) * Post-incision application of 3% hydrogen peroxide * Post-incision application of 10% povidone-iodine (betadine) * No post-incision treatment (control) The investigators hypothesize that the subjects treated with the antimicrobial solutions after initial incision will have lower rates of positive C. Acnes cultures. The investigators also hypothesize that post-incision application of Xperience Antimicrobial wash and Betadine will have an equal reduction in the incidence of C. acnes as Hydrogen Peroxide.

Participants needed: 150
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Henry Ford Health SystemUpdated: Jun 4, 2025Locations: 1
Eligibility criteria

Indicated and scheduled for primary shoulder arthroplasty. [+4]

Patient with history of prior native shoulder septic arthritis or infection [+6]