Post Operative Wound Infection

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Review clinical trials related to Post Operative Wound Infection. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Early Versus Delayed Bathing of Orthopaedic Surgical Wounds

This is a single center randomized control trial assessing the effect of early versus delayed bathing on orthopaedic surgical wounds in patients undergoing surgical treatment of fractures. Patients will be recruited by screening all patients undergoing surgical treatment for fractures at our institution. Patients who provide written consent will be randomized to one of two treatment arms after confirming eligibility criteria. Group A will be advised to begin early normal bathing (non-submerged showering) with uncovered surgical wounds. Group B will be advised to follow traditional delayed bathing with covered wounds. Those who do not wish to participate in the randomized trial will be invited to participate observationally (no randomization) and have the same prospective follow-up.

Participants needed: 56
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Hospital for Special Surgery, New YorkUpdated: Mar 30, 2026Locations: 1
Eligibility criteria

Patients over 18 years of age [+5]

Fractures associated with presumed infection [+8]

Status: Recruiting

Outcomes of High-volume Saline Irrigation VS Povidone-Iodine Solution Cleaning of IOWI in Preventing SSIs in Emergency Laparotomies

The goal of this clinical trial is to compare the outcomes of High-volume saline irrigation vs Povidone-iodine solution cleaning of the intraoperative incision wound in preventing superficial surgical site infections in patients undergoing emergency laparotomies. The main question it aims to answer are: * Incidence of SSI after intervention * Length of hospital stay Participants will be randomly assigned to two groups receiving either of the two groups: Group A: 1000ml of IOWI with saline solution prior to incision closure Group B: The incisional wound will be closed conventionally without irrigation. Researchers will compare groups A( experimental group) and B (control group) to compare the incidence of superficial surgical site infections after intervention.

Participants needed: 200
Trial details
Phase: Phase 2, Phase 3Age: 18-60Biological sex: AllType: InterventionalSponsor: Dow University of Health SciencesUpdated: Jun 18, 2025Locations: 1
Eligibility criteria

• Patients undergoing emergency laparotomy under the care of surgical-6 unit of... [+1]

Diabetic patients [+8]

Status: Not yet recruiting

Powdered Intrawound Vancomycin in Open Fractures Trial

The purpose of this randomized control trial is to compare the rate of post-operative infection in patients with open fractures in upper or lower extremity long bones randomized to receive intra-operative intrawound topical vancomycin powder on their open fractures in addition to the current best practice of intravenous antibiotics with irrigation and debridement compared to intravenous antibiotics with irrigation and debridement alone during definitive operative fixation of the fracture.

Participants needed: 350
Trial details
Phase: Phase 4Age: 18+Biological sex: AllType: InterventionalSponsor: University of ManitobaUpdated: Sep 19, 2024Locations: 1
Eligibility criteria

18 years or older at time of surgery [+3]

Patients with known vancomycin allergy, drug administration reaction, or other s... [+8]