Post-stroke Cognitive Impairment

6

Review clinical trials related to Post-stroke Cognitive Impairment. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Tele-Rehabilitation vs Conventional Rehabilitation for Cognitive Improvement in Stroke Survivors.

This study aims to: * Compare tele-rehabilitation and conventional rehabilitation for cognitive improvement after stroke. * Evaluate changes in cognitive function using standardized assessment tools. * Determine whether tele-rehabilitation is as effective as conventional therapy. * Improve evidence-based rehabilitation strategies for stroke survivors.

Participants needed: 32
Trial details
Age: 50-80Biological sex: AllType: InterventionalSponsor: Riphah International UniversityUpdated: Apr 3, 2026Locations: 1
Eligibility criteria

Adults with age 50-80 [+3]

History of neurodegenerative disorder e.g Alzheimer's Disease and Parkinson's Di... [+2]

Status: Not yet recruiting

Key Technical Research on the Treatment of Post-stroke Cognitive Impairment With Brain Electric Field Therapy Based on Acupoint Regulation

This clinical study investigates whether electroacupuncture can improve thinking and memory in people with cognitive problems after a stroke (Post-Stroke Cognitive Impairment, or PSCI). Participants will be randomly assigned to one of two groups: one group will receive real electroacupuncture, while the other will receive a sham treatment . Both groups will also receive standard medical care.The main goal is to see if the real electroacupuncture leads to greater improvement in cognitive function tests over 6 months compared to the sham treatment. The study will also use brain scans (MRI) and other assessments to understand how the treatment might work.

Participants needed: 110
Trial details
Age: 35-80Biological sex: AllType: InterventionalSponsor: Second Affiliated Hospital, School of Medicine, Zhejiang UniversityUpdated: Feb 20, 2026
Eligibility criteria

Meets diagnostic criteria for Vascular Cognitive Impairment (VCI) per the 2024 C... [+5]

Severe chronic systemic diseases (e.g., cardiac, hepatic, renal, hematologic) or... [+5]

Status: Not yet recruiting

Tridimensional Robotic Assessment of Neglect in Brain Injured Patients

The goal of this clinical trial is to assess the usability and feasibility of a robotic and virtual reality-based system called NeglectARm 3D for the three-dimensional assessment of unilateral spatial neglect (USN) in patients with brain injury due to ischemic or hemorrhagic stroke. The main questions it aims to answer are: * Is the NeglectARm 3D system usable and feasible for patients with USN? * Do the robotic measurements show preliminary reliability and validity compared with conventional clinical neglect assessments (e.g., BIT, CBS)? Participants will: * Perform two assessment sessions, three weeks apart (T0 and T1); * Interact with the NeglectARm 3D system using a robotic end-effector and a VR headset to reach sequentially presented targets in a 3D virtual space; * Receive robotic assistance if targets are not reached, allowing the system to record trajectories, spatial positions, and assistance applied; * Complete standard clinical neglect tests to enable comparison between robotic and conventional measures. This study aims to develop a repeatable, standardized, and objective tool for the assessment of USN in patients with brain injury, potentially improving evaluation of depth perception and spatial attention deficits.

Participants needed: 15
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Fondazione Don Carlo Gnocchi OnlusUpdated: Dec 18, 2025Locations: 3
Eligibility criteria

Age > 18 years; [+3]

Presence of language deficits (inability to complete the OCS test); [+8]

Status: Recruiting

Edaravone Dexborneol Sublingual Tablet for the PSCI in Acute Ischemic Stroke Patients

This is a multicenter, randomized, double-blind, placebo-controlled, exploratory Phase II clinical trial. The goal of this clinical trial is to assess the safety and efficacy of edaravone dexborneol sublingual tablets for post-stroke cognitive impairment in patients with acute ischemic stroke. Participants will be required to receive 24 weeks treatment of edaravone dexborneol sublingual tablets or placebo during this study. The safety and efficacy endpoints will be compared in the patients with edaravone dexborneol sublingual tablets or placebo.

Participants needed: 226
Trial details
Phase: Phase 2Age: 40-80Biological sex: AllType: InterventionalSponsor: Simcere Pharmaceutical Co., LtdUpdated: Sep 3, 2025Locations: 21
Eligibility criteria

Age ≥ 40 years and ≤ 80 years, male or female. [+8]

Presence of intracranial hemorrhagic disease confirmed by brain imaging. [+20]

Status: Recruiting

HOPE From the Cerebellum: TMS-Induced Cognitive Recovery After Stroke

The objective of this clinical trial is to investigate the effectiveness and safety of repetitive transcranial magnetic stimulation (rTMS) in the cerebellum for individuals with post-stroke cognitive impairment. Participants will undergo rTMS in the cerebellar hemisphere opposite the lesion site, once daily for a total of five days.

Participants needed: 70
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Zi-Xiao LiUpdated: Jul 2, 2025Locations: 1
Eligibility criteria

Not listed

Status: Not yet recruiting

Local Opera Viewing Combined Medical Gymnastics for Elderly PSCI

local opera viewing combined medical gymnastics for elderly PSCI

Participants needed: 160
Trial details
Age: 60-100Biological sex: AllType: InterventionalSponsor: Zhangzhou Municipal HospitalUpdated: Jun 13, 2024
Eligibility criteria

Other causes affect or lead to cognitive impairment, such as consciousness disor...