Status: Recruiting
Remote Ischemic Preconditioning and Postoperative Neuronal Injury
The SHIELD trial is a single-center, randomized, controlled, parallel-group, single-blinded clinical trial investigating whether performing RIPC one day before surgery-compared to not performing RIPC-reduces postoperative neuronal injury, as reflected by the maximum serum NfL concentration within the first 2 postoperative days, in non-cardiac surgery patients at risk for postoperative delirium.
Participants needed: 216
Trial details
Age: 50+Biological sex: AllType: InterventionalSponsor: University of Hamburg-EppendorfUpdated: Mar 4, 2026Locations: 1
Eligibility criteria
patients (≥50 years) scheduled for elective non-cardiac surgery with general ane... [+1]
patients in whom RIPC cannot be safely applied due to relevant peripheral arteri... [+7]