Postoperative Vomiting

4

Review clinical trials related to Postoperative Vomiting. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Advancing Strategies to Optimize the PerIopeRativE Management of PostOperative Nausea and Vomiting (ASPIRE-PONV) Trial

The goal of this prospective, unblinded, pragmatic and repeated crossover trial is to learn if clinical decision support alerts will impact postoperative nausea and vomiting (PONV) prophylaxis and reduce PONV rates in adult patients who have planned surgery with general anesthesia. The main aim is to improve PONV, establishing a scalable Clinical Decision Support (CDS) Tool for personalized PONV prevention. The primary hypothesis is that, compared with standard care, the Anesthesia Workflow-Driven Clinical Decision Support Tool for Personalized PONV Prevention will be associated with a significant improvement in the rate of appropriate administration of PONV prophylaxis and a significant decrease in the incidence of PONV. This study will evaluate a new clinical decision support (CDS) tool designed to improve how and when PONV prevention strategies are used. Unlike traditional tools that provide generic, one-time alerts, this new system is integrated into the electronic health record (EHR) and delivers timely, targeted reminders to anesthesia providers at key moments during a patient's surgical care-such as before surgery begins, after anesthesia is given, and before the patient wakes up. These alerts are based on each patient's individual risk for PONV and are intended to support, not replace, clinical judgment. The study will use a crossover design over 12 months, alternating between periods when the tool is active and when it is not. The goal is to determine whether this time-sensitive, workflow-integrated tool can lead to better adherence to best practices and improved patient outcomes.

Participants needed: 19,480
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Vanderbilt University Medical CenterUpdated: Jan 12, 2026Locations: 1
Eligibility criteria

Planned surgery with general anesthesia with endotracheal intubation or laryngea... [+1]

ASA 6 including organ procurement, [+6]

Status: Not yet recruiting

Comparison of Two Plane Blocks Used in Open Ventral Hernia Repair Operations

The aim of this study is to compare the postoperative analgesic efficacy of bilateral erector spinae plane block and bilateral external oblique-intercostal plane block in patients undergoing open ventral hernia repair.

Participants needed: 50
Trial details
Age: 18-65Biological sex: AllType: InterventionalSponsor: Ankara Ataturk Sanatorium Training and Research HospitalUpdated: Sep 16, 2025Locations: 1
Eligibility criteria

Patients scheduled for open ventral hernia repair under general anesthesia [+2]

Patients scheduled for open ventral hernia repair under spinal or epidural anest... [+5]

Status: Recruiting

Intraoperative Autonomic Blockade for Laparoscopic Cholecystectomy

This study proposes infiltrating the hepatoduodenal ligament and the serosal reflection of the gallbladder cystic plate with a combination of Bupivacaine (a long-acting local anesthetic) and Dexamethasone (a corticosteroid). This technique aims to block the hepatic branches of the celiac plexus to improve visceral pain control and its associated clinical manifestations, reduce analgesic requirements, and lower readmission rates, thereby facilitating recovery.

Participants needed: 60
Trial details
Phase: Phase 4Age: 18+Biological sex: AllType: InterventionalSponsor: Universidad Simón BolívarUpdated: Jan 28, 2025Locations: 2
Eligibility criteria

Elective or emergency laparoscopic cholecystectomy for cholelithiasis with or wi...

Associated biliary pathologies (e.g., biliary pancreatitis, cholangitis). [+3]

Status: Recruiting

The Impact of Nasogastric Tube Gastric Decompression on Postoperative Nausea and Vomiting in Orthognathic Surgery

This study will compare the incidence of postoperative nausea and vomiting during the first 24 hours following corrective jaw surgery (orthognathic surgery) in patients with and without nasogastric tube gastric decompression.

Participants needed: 92
Trial details
Age: 16+Biological sex: AllType: InterventionalSponsor: Nova Scotia Health AuthorityUpdated: Jan 14, 2025Locations: 1
Eligibility criteria

Patients over the age of 16 at the time of consent undergoing orthognathic surge... [+3]

Patients under the age of 16 at the time of consent. [+4]