Postpartum Period

14

Review clinical trials related to Postpartum Period. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Postnatal Debriefing After Adverse Obstetric Events

Adverse or unexpected obstetric events can negatively affect women's psychological well-being and childbirth experience, increasing the risk of postpartum traumatic stress. However, structured postnatal debriefing is not routinely implemented in clinical practice, and evidence regarding its effectiveness remains limited. This study aims to evaluate the effect of a structured postnatal debriefing conducted within the first 24 hours after childbirth in women who have experienced an adverse or unexpected obstetric event. This quasi-experimental pretest-posttest study will include two consecutive groups: a control group receiving usual postpartum care during the pre-implementation phase and an intervention group receiving structured postnatal debriefing during the implementation phase. The primary outcome is childbirth-related trauma at 6 weeks postpartum. Secondary outcomes include birth satisfaction, early post-traumatic stress symptoms, satisfaction with information and emotional support received after childbirth, and clinical maternal and neonatal outcomes. This study will provide evidence on whether structured postnatal debriefing improves psychological outcomes and contributes to more patient-centered obstetric care.

Participants needed: 142
Trial details
Age: 18+Biological sex: FemaleType: InterventionalSponsor: Parc de Salut MarUpdated: Jun 25, 2026
Eligibility criteria

Women aged 18 years or older. [+5]

Inability to communicate verbally. [+4]

Status: Recruiting

Evaluation of Blood Loss After Cesarean Delivery Via US Compared to Standard Care

Postpartum hemorrhage and anemia are considered a major health concern due to their impact on maternal morbidity and mortality, quality of life, and maternal cognitive and emotional functioning after delivery, which are particularly important during the critical period of mother-child bonding. Hemoglobin levels in the first 24 hours after delivery do not reflect the lowest point (nadir). The postpartum nadir occurs 48-72 hours after delivery due to the initial redistribution of plasma volume. The aim of this study was to examine whether postpartum ultrasound examination precedes laboratory test results in the diagnosis of anemia due to blood loss after cesarean section.

Participants needed: 276
Trial details
Age: 18-50Biological sex: FemaleType: InterventionalSponsor: Holy Family Hospital, Nazareth, IsraelUpdated: Jun 16, 2026Locations: 1
Eligibility criteria

Women who delivered by a cesarean section. [+3]

Lack of consent or inability to provide informed consent. [+3]

Status: Not yet recruiting

THE EFFECT OF REIKI APPLIED DURING THE POSTPARTUM PERIOD ON THE QUALITY OF POSTPARTUM RECOVERY, COMFORT AND MOOD.

The postpartum period, also defined as the fourth trimester of pregnancy, encompasses the approximately 6-8 week period following childbirth, during which the organs that underwent changes during pregnancy return to their previous state. This period is of great importance in terms of protecting the health of both mother and baby, meeting their care needs, and increasing their comfort. During the postpartum period, women experience physiological, psychological, and social changes; hormonal changes, assuming parental roles, changes in family dynamics, and increased responsibilities related to infant care can lead to adjustment difficulties. This can cause problems for the mother in both her own care and infant care. In the postpartum period, mothers may experience various health problems such as pain, fatigue, sleep disturbances, infections, breastfeeding problems, hemorrhoids, constipation, urinary incontinence, depressive symptoms, and mood swings. Pain, in particular, arises due to uterine contractions, breast engorgement, nipple tenderness, and other complications, negatively affecting the mother's mobility, sleep patterns, social interaction, and quality of life. Furthermore, stress and adjustment problems experienced during the postpartum period can lead to serious psychological problems such as delayed maternal bonding, postpartum blues, postpartum depression, psychosis, and communication problems between couples. Pharmacological and non-pharmacological methods are used in the management of these problems. However, due to the negative effects that pharmacological methods may have during breastfeeding, interest in complementary and alternative medicine practices has increased. Reflexology, aromatherapy, music therapy, acupressure, and Reiki are among these methods. Reiki is an energy therapy method that aims to balance an individual's life energy and support the natural healing process, applied through touch or the placement of hands on specific points. Reiki application is reported to have positive effects on pain, stress, anxiety, sleep quality, and coping skills. Although it is one of the preferred methods for adapting to changes and reducing problems experienced in the postpartum period, studies directly examining the effects of Reiki application on postpartum recovery quality, comfort, and mood are quite limited. Due to its low cost, ease of application, and lack of side effects, Reiki is considered an important complementary care approach that can be used in the postpartum period. The aim of this study is to determine the effect of face-to-face Reiki treatment on the quality of postpartum healing, comfort level, and mood in women who have had cesarean deliveries, on days 1, 2, and 7 of the postpartum period.

Participants needed: 80
Trial details
Age: 19-35Biological sex: FemaleType: InterventionalSponsor: University of GaziantepUpdated: Jun 17, 2026
Eligibility criteria

Ages 19-35 [+6]

Having an infectious skin disease [+6]

Status: Recruiting

Effects of Pilates and Moderate-Intensity Aerobic Exercise on Postpartum Weight Loss and Body Composition

After childbirth, many women experience difficulty losing pregnancy-related weight, which can affect their health, self-esteem, and physical activity. Regular exercise, including Pilates and moderate-intensity aerobic exercises, is considered a safe and natural method to improve fitness and support weight loss during the postpartum period. This study aims to compare the effects of Pilates and aerobic exercise on body weight, Body Mass Index (BMI), and waist-to-hip ratio in postpartum women over 8 weeks. Participants will be randomly assigned to either a Pilates group or an aerobic exercise group, with both groups exercising three times weekly for 45-60 minutes. The results will then be compared to determine which exercise method is more effective.

Participants needed: 30
Trial details
Age: 20-40Biological sex: FemaleType: InterventionalSponsor: Riphah International UniversityUpdated: Jun 11, 2026Locations: 1
Eligibility criteria

Women aged 20 to 40 years [+3]

Women with complications during delivery (Cesarean complications, perineal tears... [+4]

Status: Recruiting

Postpartum Acupressure Education and Breastfeeding Outcomes

This randomized controlled trial evaluates whether acupressure education provided to mothers within the first 48 hours postpartum improves exclusive breastfeeding rates at 6 months compared with standard postpartum care alone. Mothers in the intervention group will receive structured education on self-administered acupressure at selected points and will be encouraged to continue home-based practice, while the control group will receive standard breastfeeding support. Participants will be followed for 12 months to assess breastfeeding continuation, breastfeeding self-efficacy, breastfeeding quality, and breastfeeding-related outcomes.

Participants needed: 360
Trial details
Age: 18-45Biological sex: FemaleType: InterventionalSponsor: Nigde Omer Halisdemir UniversityUpdated: Jun 2, 2026Locations: 1
Eligibility criteria

Age 18 to 45 years [+6]

Contraindications to breastfeeding (e.g., infant galactosemia) [+5]

Status: Not yet recruiting

Skin-to-Skin Contact and Lavender Aromatherapy After Elective Cesarean: Effects on Cortisol and Early Breastfeeding

This single-center randomized controlled clinical trial will evaluate the effects of structured early postpartum mother-infant skin-to-skin contact, with or without maternal lavender aromatherapy, after elective cesarean section on maternal stress biomarkers and early breastfeeding outcomes. The study will enroll 150 term pregnant women scheduled for elective cesarean section under spinal anesthesia at Ataturk University Research Hospital. Participants will be randomized into three groups: routine postoperative care, structured skin-to-skin contact, and structured skin-to-skin contact combined with inhalational lavender aromatherapy. The primary outcome is the change in maternal salivary cortisol level from immediately after birth to 60 minutes postpartum. Secondary outcomes include maternal salivary IgA levels, state anxiety scores, postoperative pain and nausea, time to first analgesic requirement, early breastfeeding initiation and success, LATCH scores, neonatal axillary temperature, cumulative duration and continuity of skin-to-skin contact, maternal satisfaction, and the need for mother-infant separation within the first 2 hours postpartum.

Participants needed: 150
Trial details
Age: 18-40Biological sex: FemaleType: InterventionalSponsor: Ataturk UniversityUpdated: May 28, 2026Locations: 1
Eligibility criteria

Female participants aged 18 to 40 years [+7]

Emergency cesarean section [+11]

Status: Not yet recruiting

Therapeutic Exercise for Postpartum Recovery

Pelvic floor dysfunctions (PFDs) are common conditions that affect women, especially after vaginal childbirth. These disorders can cause urinary or fecal incontinence, pain during sexual activity, and prolapse of pelvic organs, leading to a significant decrease in quality of life. Current scientific evidence shows that early and specific physiotherapy-based interventions after childbirth may help reduce the risk of developing long-term PFDs. Pelvic floor muscle training (PFMT) is currently the first-line conservative treatment for women with PFD, but in recent years other exercise methods, such as hypopressive exercises, have become increasingly popular, despite limited supporting evidence. At the same time, some women need to return early to physically demanding jobs or impact sports, but there are no clear guidelines on how to safely prepare the abdominopelvic region for progressive exposure to increased intra-abdominal pressure. This study aims to compare two postpartum recovery exercise programs: A program based on lumbopelvic stabilization exercises that progressively expose women to increases in intra-abdominal pressure and impact activities. A program based on hypopressive exercises, which focus on avoiding intra-abdominal pressure. The goal is to determine which approach is safer and more effective in improving pelvic floor recovery after childbirth and in supporting women in their gradual return to daily, work, and sports activities.

Participants needed: 84
Trial details
Age: 18+Biological sex: FemaleType: InterventionalSponsor: University of AlcalaUpdated: May 4, 2026Locations: 1
Eligibility criteria

Primiparous or multiparous women with an uncomplicated vaginal delivery. [+2]

Cesarean delivery. [+11]

Status: Recruiting

The PreEclampsia Postpartum Prevention Trial

The goal of this clinical trial is to learn if a postpartum bundle intervention can improve cardiometabolic health and lifestyle-related factors in women who have had preeclampsia during their first pregnancy. The main questions it aims to answer are: * Does the 9-month intervention reduce systolic and diastolic blood pressure? * Does the intervention promote postpartum weight loss? * Does the intervention affect weight and blood pressure depending on early pregnancy BMI? Researchers will compare the bundle intervention to standard care to see if the intervention improves cardiometabolic health and lifestyle outcomes. All participants will attend clinical visits for outcome assessments. Participants in the intervention group will: * Receive online targeted screening and group meetings with study personnel * Use the trial-specific PEPP app to access self-monitoring tools for blood pressure and weight, lifestyle modification, and health education * Follow the intervention in two phases: starting after inclusion (≈8 weeks postpartum) with a Light phase (baseline-3 months) and progressing to an Intensive phase (3-9 months)

Participants needed: 356
Trial details
Age: 18+Biological sex: FemaleType: InterventionalSponsor: Karolinska InstitutetUpdated: May 4, 2026Locations: 2
Eligibility criteria

First-time mothers postpartum [+6]

Pre-pregnancy hypertension [+7]

Status: Not yet recruiting

Midwife-Led Digital Follow-Up After Cesarean Section

This randomized controlled trial aims to evaluate the effect of a midwife-led digital follow-up program on postpartum depression, perceived social support, and breastfeeding self-efficacy in women who will undergo cesarean section. Participants will be randomly assigned to either an intervention group that will receive structured face-to-face education followed by a 4-week digital follow-up program, or a control group that will receive routine postpartum care. Data will be collected at baseline (postpartum day 1), at 1 week, and at 4 weeks postpartum using validated measurement tools. The study will provide evidence on the effectiveness of continuous, midwife-led digital support in improving maternal psychological well-being and breastfeeding outcomes in the early postpartum period.

Participants needed: 104
Trial details
Age: 18-45Biological sex: FemaleType: InterventionalSponsor: Inonu UniversityUpdated: Apr 16, 2026Locations: 1
Eligibility criteria

Women aged between 18 and 45 years [+5]

History of psychiatric disorders [+4]

Status: Not yet recruiting

Short-Term Mindfulness Intervention for Anxiety and Maternal Attachment in NICU Mothers

This randomized controlled study aims to evaluate the effects of a short-term mindfulness-based stress reduction (MBSR) program on anxiety levels and maternal attachment in mothers whose infants are admitted to the Neonatal Intensive Care Unit (NICU). A total of 33 mothers will be recruited and assigned to intervention and control groups. The intervention group will receive a structured four-session mindfulness program, while the control group will receive standard care. Data will be collected using the Maternal Attachment Scale and the State-Trait Anxiety Inventory. The findings are expected to provide evidence on the effectiveness of mindfulness-based interventions in reducing anxiety and improving maternal-infant bonding during the postpartum period.

Participants needed: 66
Trial details
Age: 18-50Biological sex: FemaleType: InterventionalSponsor: Saglik Bilimleri UniversitesiUpdated: Apr 9, 2026
Eligibility criteria

Not listed

Status: Recruiting

Relationship Between the Severity of Sleep Deprivation in the First 48 Hours Postpartum, Breastfeeding Motivation, and Breastfeeding Success

The postpartum period is a critical time marked by significant physiological and psychosocial changes that can affect sleep, emotional well-being, and breastfeeding behaviors. Previous studies indicate that mode of delivery and sleep quality are closely associated with breastfeeding outcomes, with cesarean birth often linked to poorer sleep and lower breastfeeding success. Evidence also suggests that postpartum sleep disturbances are related to reduced breastfeeding self-efficacy, lower motivation, fatigue, depressive symptoms, and shorter breastfeeding duration. However, the literature lacks studies that evaluate insomnia severity, breastfeeding motivation, and breastfeeding success simultaneously-particularly during the first 48 hours after birth. This analytical study aims to assess insomnia severity, breastfeeding motivation, and breastfeeding success (LATCH) within the first 48 postpartum hours and to examine the relationships among these variables. Findings are expected to support early postpartum clinical interventions to improve maternal and infant health outcomes.

Participants needed: 167
Trial details
Age: 18+Biological sex: FemaleType: ObservationalSponsor: Acibadem UniversityUpdated: Mar 24, 2026Locations: 1
Eligibility criteria

Primiparous or multiparous women aged 18 years and older [+3]

Complications requiring sedation [+2]

Status: Recruiting

Association of Spousal Support With Parenting Self-Confidence and Depression in Primipar Mothers

The transition to motherhood, particularly for first-time (primiparous) women, is a critical life period requiring substantial psychological and social adjustment. Hormonal changes, increased caregiving responsibilities, sleep disturbances, and potential social isolation during pregnancy and the postpartum period may increase vulnerability to stress, anxiety, and depressive symptoms. Postpartum depression (PPD) is a common mental health concern that adversely affects maternal well-being, mother-infant interaction, and infant development, with insufficient social support identified as one of its most significant risk factors. Maternal self-efficacy, defined as a mother's perceived competence in caring for and responding to her infant's needs, is a key indicator of successful adaptation to the parenting role. Evidence suggests that maternal self-efficacy develops primarily within the first months after childbirth and tends to be lower in primiparous women. Low parenting self-efficacy has been associated with increased depressive symptoms, higher parenting stress, impaired mother-infant bonding, and negative developmental outcomes for the infant. Among social support sources, partner support plays a particularly protective role during the transition to parenthood. Emotional, informational, and practical support provided by the partner has been shown to enhance maternal self-efficacy, reduce psychological distress, improve marital adjustment, and lower the risk of postpartum depression. Conversely, low perceived partner support and relationship difficulties are associated with an increased risk of PPD in primiparous mothers. The aim of this study is to examine the relationship between perceived partner support and postpartum parenting self-efficacy and depressive symptoms in primiparous women. Additionally, the study seeks to evaluate the explanatory and protective role of partner support on maternal self-efficacy and postpartum depression during the early postpartum period.

Participants needed: 193
Trial details
Age: 18+Biological sex: FemaleType: ObservationalSponsor: Istanbul University - CerrahpasaUpdated: Feb 3, 2026Locations: 1
Eligibility criteria

Aged 18 years or older [+6]

Diagnosed neurological disorder [+3]

Status: Recruiting

The Effect of Motivational Interviewing and Digital Game-Supported Counseling on Postpartum Relapse

This randomized controlled trial aims to determine the effect of motivational interviewing-based, digital game-supported counseling on postpartum smoking relapse among pregnant women who quit smoking spontaneously during pregnancy. Women who smoked at least one cigarette per day before pregnancy and quit smoking during pregnancy will be included. Participants will be randomly assigned to two groups: in the intervention group, online motivational interviewing sessions will be delivered once each during the third and fourth prenatal follow-ups by the researcher, and a digital game assignment will be provided after each session; the control group will receive routine health counseling delivered during prenatal follow-ups. The primary outcome measure is the rate of smoking relapse at three months postpartum. Secondary outcome measures include the postpartum slip rate, craving to smoke, and motivation to remain abstinent.

Participants needed: 72
Trial details
Age: 18+Biological sex: FemaleType: InterventionalSponsor: Lokman Hekim UniversityUpdated: Dec 9, 2025Locations: 1
Eligibility criteria

Aged ≥18 years [+5]

Having a diagnosis of any psychiatric disorder [+6]

Status: Not yet recruiting

The PARTUM Trial: Postpartum Aspirin to Reduce Thromboembolism Undue Morbidity

The goal of the PARTUM trial is to determine if taking low-dose aspirin daily for 6 weeks after delivery is similar (non-inferior) to usual care low-molecular-weight heparin injections to prevent venous thromboembolism (VTE: blood clots in the legs or lungs) for postpartum individuals with VTE risk factors.

Participants needed: 8,805
Trial details
Phase: Phase 3Age: 18+Biological sex: FemaleType: InterventionalSponsor: University of CalgaryUpdated: Mar 3, 2025Locations: 3
Eligibility criteria

Antepartum immobilization for ≥7 days. Immobilization is defined as bed rest wit... [+9]

More than 48 hours since delivery at the time of randomization [+11]