Premature Loss of Primary Molars

2

Review clinical trials related to Premature Loss of Primary Molars. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Clinical Safety Guidelines for Managing Distal Shoe Complications

Distal shoe space maintainers are the standard of care for guiding the eruption of permanent first molars following the premature loss of the primary second molars. Although this therapy represents established clinical practice, prospective evidence regarding soft tissue complications and predictors of treatment outcomes remains limited. This observational study will prospectively collect clinical outcome data during routine treatment visits. The aims of the study are to characterize patterns of complications, evaluate outcomes related to patient adherence, and identify predictors of treatment success. Ultimately, this study seeks to support the development of standardized strategies for clinical monitoring and complication management.

Participants needed: 50
Trial details
Age: 3-9Biological sex: AllType: ObservationalSponsor: University of FloridaUpdated: May 12, 2026Locations: 2
Eligibility criteria

Pediatric participants aged 3 to 9 years [+4]

Presence of systemic medical conditions that may affect bone metabolism or wound... [+2]

Status: Not yet recruiting

Space Changes After Premature Loss of Lower First Primary Molars in Children Using Digital Scanning

This prospective split-mouth clinical study aims to evaluate space changes in the mandibular dental arch following premature extraction of the lower first primary molar in children aged 3 to 5.5 years. Using digital 3D models, changes in the D space and mandibular arch perimeter will be measured at baseline and 6 months post-extraction. The goal is to determine whether space maintainers are necessary in the primary dentition stage.

Participants needed: 11
Trial details
Age: 3-66Biological sex: AllType: ObservationalSponsor: Cairo UniversityUpdated: May 14, 2025Locations: 1
Eligibility criteria

Children aged 3 to 5.5 years [+6]

Bilateral premature loss of mandibular first primary molars [+5]