Premature Menopause

2

Review clinical trials related to Premature Menopause. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Improving Outcomes in Early Menopause After Cancer

The goal of this study is to create and test a new program led by nurse navigators to help women who experience early menopause after cancer. The program includes personalized menopause education, decision support, and skills to manage menopause symptoms. The main questions it aims to answer are: 1. Is the program easy to join, engaging, and well-received by participants? 2. Does the program group show greater improvements in knowledge, decision-making, confidence, and menopause symptom management compared to the control group? Participants will complete sessions of either the program being tested or an educational control program with a nurse navigator via video. Participants will also complete questionnaires when they start the study and again about 10 weeks later.

Participants needed: 117
Trial details
Age: 18-44Biological sex: FemaleType: InterventionalSponsor: Duke UniversityUpdated: May 14, 2026Locations: 1
Eligibility criteria

female (biological sex); [+4]

diagnosis of metastatic cancer; [+2]

Status: Not yet recruiting

Effects of Estrogen on Heart Health in Women With Primary Ovarian Insufficiency

The goal of this observational study is to study the effects of treating women with Primary Ovarian Insufficiency (POI) with estrogen replacement therapy to bolster the evidence backing cardiometabolic preventive care in women with POI. The main question it aims to answer is: Does 6 months of estrogen replacement therapy for women with POI improved markers of heart health? Women newly diagnosed with POI (within 6 months) who are planning to start estrogen replacement therapy from their clinical provider will undergo assessment of markers of heart health before and after 6 months of treatment. These markers will also be compared to those obtained from healthy women without POI.

Participants needed: 45
Trial details
Age: 30-40Biological sex: FemaleType: ObservationalSponsor: Massachusetts General HospitalUpdated: Jan 7, 2026Locations: 1
Eligibility criteria

female sex [+4]

CASE PARTICIPANTS ONLY: genetic POI etiology [+18]