Pressure Injuries

12

Review clinical trials related to Pressure Injuries. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Manual Lymphatic Drainage on Pressure Injuries

Pressure injuries are a significant health problem, often resulting from pressure, friction, and impaired tissue perfusion, and are particularly common in individuals in intensive care, those with immobility, and those with chronic diseases. The literature extensively addresses interventions such as pressure reduction, the use of appropriate support surfaces, wound care practices, and nutritional support in the prevention and treatment of pressure injuries. However, the role of manual therapies aimed at improving circulation and lymphatic flow, such as manual lymphatic drainage (MLD), in pressure injuries has been examined in a limited number of studies. This research aims to fill a significant gap in the literature by evaluating the potential effects of manual lymphatic drainage on reducing edema, improving tissue perfusion, and supporting the wound healing process in individuals with pressure injuries.

Participants needed: 60
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Rukiye KokkizUpdated: Jul 1, 2026
Eligibility criteria

Presence of pressure injury in the sacrum region [+3]

Chronic illness that may affect pressure injury healing (malnutrition, hypertens... [+7]

Status: Not yet recruiting

AI-Based Wound Monitoring: Automated Wound Progression Assessment Via Marker-Free Image Sequence

This study aims to develop a low-cost, marker-free intelligent wound assessment system that can analyze wound photos taken with a standard smartphone. By comparing wound images over time, the system will generate a quantifiable Wound Progression Index (WPI) to provide objective feedback on whether a wound is improving, stable, or worsening. The long-term goal is to support early detection of wound deterioration and improve wound care in both clinical and home settings.

Participants needed: 1,000
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: National Taiwan University HospitalUpdated: Jun 2, 2026Locations: 1
Eligibility criteria

(1) Presence of a hard-to-heal wound that has remained unhealed for more than on...

Wounds whose margins could not be fully included within the imaging field.

Status: Not yet recruiting

Barrier Functions oF Skin in ICU: SKIN-BAR

This study aims to investigate skin barrier function in intensive care unit (ICU) patients using biosensor-based measurements. Biophysical parameters including transepidermal water loss (TEWL), skin pH, stratum corneum hydration, local skin temperature, and sebum will be assessed in anatomical regions at risk for pressure injuries. The study will examine temporal changes in these parameters, their interrelationships, and their association with pressure injury development.

Participants needed: 156
Trial details
Age: 18+Biological sex: AllType: ObservationalSponsor: Koç UniversityUpdated: May 1, 2026Locations: 1
Eligibility criteria

Adults aged >18 years [+5]

Inability to tolerate position changes [+5]

Status: Recruiting

Evaluate the Feasibility and Effectiveness of a Community-based Care Bundle in Managing and Preventing Pressure Injuries

Community-acquired pressure injuries are pressure injuries that developed outside of hospital, typically in the patient's own home environment. Pressure injuries (PI) used to be commonly known as bedsores or pressure ulcers. The goal of this clinical trial is to evaluate if a community-based pressure injury (PI) care bundle is effective in treating and preventing pressure injuries in home settings. It will also assess how feasible it is to implement this care bundle in Singapore's community care context. The main questions it aims to answer are: 1. Does the PI care bundle help improve pressure injury healing (shown by at least a 3-point reduction on the PUSH score)? 2. Can the care bundle prevent the development of new pressure injuries? 3. How well do caregivers learn and apply PI care knowledge after receiving the educational intervention? 4. How practical and acceptable is this care bundle for use in home settings? The investigators will compare the PI care bundle to routine care (control group) to see if the care bundle works better for managing pressure injuries at home. Success will be measured using the PUSH tool, which scores pressure injuries from 0 (completely healed) to 17 (most severe). A reduction of at least 3 points on this scale will indicate meaningful improvement. Participants and their caregivers will: Be split into two groups - one group will use the new care plan (receive the PI care bundle), and the other will continue with their routine care. Have their pressure injuries checked regularly for 6 weeks. Have their caregivers learn about pressure injury care. Answer questions about how well the care plan works for them. The investigator hopes this study will help find better ways to treat or prevent pressure injuries at home and support the caregivers at home.

Participants needed: 216
Trial details
Age: 21+Biological sex: AllType: InterventionalSponsor: Singapore General HospitalUpdated: Apr 29, 2026Locations: 2
Eligibility criteria

adult patients discharged from SGH with existing PI (any stages according to NPI... [+3]

previous or existing participation in this trial [+4]

Status: Recruiting

Physical Therapy Wound Care Modalities in Patients With Spinal Cord Injury (SCI)

To examine the effects of Physical Therapist (PT) wound care modalities (pulsed wound irrigation (PWI) + electrical stimulation (ES), PWI only, and ES only) on wound healing in patients with spinal cord injuries (SCI).

Participants needed: 40
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Wake Forest University Health SciencesUpdated: Apr 8, 2026Locations: 1
Eligibility criteria

Currently enrolled at inpatient rehabilitation at Carolinas Rehabilitation Charl... [+6]

Pain which limits ability to tolerate wound care treatments [+3]

Status: Recruiting

Effectiveness of an Online Interactive E-book in Enhancing Home Care Nurses' Knowledge, Perceived Barriers, and Self-efficacy in Home Pressure Injury Care

The goal of this study is to learn if an interactive e-book helps home care nurses improve their skills in managing pressure injuries at home. It will also learn if digital learning can overcome the challenges of traditional training. The main questions it aims to answer are: 1. Does the e-book increase home care nurses' knowledge about pressure injury prevention and treatment? 2. Does it improve their confidence and reduce the barriers they face when providing wound care? 3. How long do the learning benefits last after completing the program? Researchers will compare an interactive e-book to standard PDF training materials from the Ministry of Health and Welfare (MOHW) to see which is more effective for nursing education. Participants will: 1. Use an online interactive e-book covering 11 units of wound care for 1 month 2. Use standard PDF training materials from the MOHW Long-term Care section 3. Complete surveys about their knowledge and skills before the study, immediately after the program, and 1 month later Expected Outcomes and Contributions: This study aims to solve the problem of nursing shortages and training difficulties in rural areas. The researchers expect that home care nurses will become more competent in wound management, leading to better patient health and fewer hospital readmissions. These results will support Taiwan's "Long-term Care 3.0" policy by driving innovation in digital education.

Participants needed: 132
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Kaohsiung Medical UniversityUpdated: Mar 17, 2026Locations: 1
Eligibility criteria

Registered nurses aged 18 years or older. [+3]

Home care nurses who hold specialized certifications related to advanced wound c... [+1]

Status: Not yet recruiting

Using Music During Wound Care Among Seniors With Pressure Injuries

Pressure injuries (also known as pressure wounds or bed sores) are increasingly common among older adults living in care homes. These wounds often require regular dressing changes, which can be uncomfortable for some. The researchers believe that listening to music during wound care may have an effect on pain, wound healing, and the overall wound care experience, compared with wound care without music. The goal of this clinical study is to test this idea by examining whether listening to music before and during wound care is linked to differences in pain, wound healing, and the overall wound care experience in older adults with pressure injuries. The main questions this study aims to answer are: Does listening to music before and during pressure injury care affect pain during wound care? Does listening to music before and during pressure injury care affect how pressure injuries heal over time? Does listening to music affect the overall experience of pressure injury care? Researchers will compare wound care with music to wound care without music to better understand whether music makes a difference. The study will take place in eleven long-term care homes in Ontario. Participants will be residents aged 60 years and older who have a stage II, III, or IV pressure injury and who are already receiving regular wound care as part of their usual care. This study will not include residents who have infected or necrotic wounds, or who are at the end of life. Participants will continue to receive the same wound care they would normally receive. Some homes will include music during wound care, and some homes will not. Participants in homes using music will: Listen to a playlist of music they personally enjoy for about 15 minutes before wound care begins Continue listening to the music during the wound care procedure Be able to change the volume or stop the music at any time Participants in homes not using music will receive the same standard pressure injury care without music. Information for the study will come from clinical records that nurses already complete during routine wound care, such as notes about pain and wound healing. Staff involved in playing the music will also complete a short questionnaire about their observations of the wound care experience. Photos of wounds that are already taken as part of usual care may be reviewed to look at healing over time. Participants may take part in the study for up to six months or until their wound has healed. Taking part is voluntary, and participants or their decision-makers can choose to stop at any time. The study does not change the medical care participants receive.

Participants needed: 50
Trial details
Age: 60+Biological sex: AllType: InterventionalSponsor: McMaster UniversityUpdated: Mar 6, 2026Locations: 11
Eligibility criteria

60 years or older [+1]

Designated as end of life and/or has a Kennedy terminal pressure injury [+5]

Status: Recruiting

Prevention of Pressure Injury (PI) in Hospitalised Infants, Children, and Young People (CYP) (Aged 0-19 Years)

What is the problem? Children and young people admitted to hospital can sometimes be harmed by what is called a pressure injury. Pressure injuries are sores (ulcers) that happen on areas of the skin that are under pressure. The pressure can come from lying in bed, sitting in a wheelchair, or wearing a cast for a long time. They usually form on bony parts of the body, such as the heels, elbows, hips, and tailbone. This can be uncomfortable for the patient and distressing for their families. As well, it means that more staff and treatments are needed for the patient. What is known? There is a difference in pressure injury seriousness for infants and children with dark skin tones to those without. Pressure injury care for hospitalised patients starts with an assessment using a tool. In the past, the assessment tools were developed without consideration for differences due to skin tone. This means that the current tools may not be the best way to identify pressure injury for dark skin tones. Healthcare professionals need to make sure that tools are fit for purpose for all. What are investigators going to do? Investigators will work with healthcare professionals, children, and parents together to develop and test the existing pressure injury risk assessment tool for use with dark skin tones. This study is a result of care priority discussions with parents and children. It came from the patients and will benefit the patients. Children, young people, and parents will be involved throughout to ensure their voices are heard. How are investigators going to do it? Investigators will: 1. Look at existing information about pressure injury for children with darker skin tones. If required, investigators will change and increase the accuracy of the existing tool. 2. Test the modified risk assessment tool at 10 children's hospitals in the UK. Investigators will do this to see if it can distinguish hospitalised children with dark skin tones, at high or low risk of pressure injury development during their hospital stay.

Participants needed: 542
Trial details
Biological sex: AllType: ObservationalSponsor: Nottingham University Hospitals NHS TrustUpdated: Dec 26, 2025Locations: 1
Eligibility criteria

Experts (e.g. tissue viability practitioners, dermatologist) [+10]

HCP not working with hospitalised infants and CYP. [+5]

Status: Recruiting

Adhesive Devices Versus Elastic Devices for Urinary Catheter Securement in Critically Ill Patients Experimental Study

Nowadays there are two types of urinary catheter securement devices, adhesive and elastic bands. The goal of this clinical trial is to determine which type of device-adhesive or elastic-is more effective for securing urinary catheters in critically ill patients. The study also aims to evaluate the prevention of urethral meatus injuries, patient discomfort, and the incidence of catheter-associated urinary tract infections . The main questions the trial aims to answer are: * Which device type better prevents injuries to the urethral meatus? * Which device reduces discomfort for patients? * Which device lowers the incidence of catheter-associated urinary tract infections? Participants will: * Use either an adhesive or an elastic device to secure their urinary catheter during their stay in critical care * Be monitored regularly to assess any injuries, discomfort, or infections related to the catheter * Provide feedback on their comfort and any complications experienced, if they are able to communicate

Participants needed: 188
Trial details
Age: 18-99Biological sex: AllType: InterventionalSponsor: Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant PauUpdated: Dec 10, 2025Locations: 1
Eligibility criteria

Age > 18 years [+3]

Known allergy to adhesive tape [+3]

Status: Not yet recruiting

Virtual Escape Room Game About Medical Device in Nurses

The research was planned as a pre-test-post-test single-group, quasi-experimental design in order to develop a web-based digital education game to improve nurses' knowledge level on pressure injuries related to medical devices and to evaluate the effect of the developed game on nurses' knowledge acquisition on pressure injuries related to medical devices, as well as the use of the game and user experience. The sample of the research will consist of nurses working in the intensive care unit at Kahramanmaraş Necip Fazıl City Hospital who meet the research criteria and agree to participate in the research. In the first stage of the research, the materials necessary for the game development and evaluation process will be prepared and the content validity study of these materials will be conducted. In the second stage, the development and preliminary evaluation of the virtual escape room game will be done. In the third stage, the virtual escape room game will be applied and data will be collected. Data will be collected from the nurses with the 'Introductory Features Form' and the 'Medical Device Related Pressure Injury Knowledge Level Assessment Test' (pre-test) before the game application; and after the game application, the 'Medical Device Related Pressure Injury Knowledge Level Assessment Test' (post-test) and the Virtual Escape Room Game Evaluation Form. After 4 weeks of the game application (retest), nurses will be asked to answer the questions of the 'Medical Device-Related Pressure Injury Knowledge Level Assessment Test'. H1a: What is the effect of the virtual escape room game on nurses' knowledge levels regarding TCBBY? H1b: What are the usage and user experiences of the virtual escape room game developed for the purpose of educating nurses on the prevention of TCBBY?

Participants needed: 60
Trial details
Biological sex: AllType: InterventionalSponsor: Kahramanmaraş İstiklal UniversityUpdated: Jul 23, 2025Locations: 1
Eligibility criteria

Volunteering to participate in the study [+3]

Not completing data collection forms or providing incomplete answers. [+1]

Status: Not yet recruiting

Gamified Learning for Pressure Injury Prevention

The goal of this Randomized Controlled Trial is to define the effect of gamified teaching methods for pressure injury prevention in intensive care nurses. The main questions it aims to answer are: H1: The gamified learning experience will increase the nurses' knowledge of pressure injury prevention compared to the control group. H2: The gamified learning experience will increase the nurses' skills in pressure injury prevention compared to the control group. H3: The gamified learning experience will increase the nurses' attitude toward pressure injury prevention compared to the control group. Researchers will compare two arm to see if there is a difference in knowledge, skills, and attitudes. Participants in the experimental group will be educated via a gamified mobile learning application.

Participants needed: 60
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Mehmet Akif Ersoy UniversityUpdated: Jun 19, 2025Locations: 1
Eligibility criteria

Being Registered Nurse for more than 1 year [+3]

Status: Recruiting

Pressure Injuries in the Operating Room and Their Perioperative Incidence in Patients Undergoing Neurosurgery.

This research project is a descriptive, longitudinal prospective observational study in the HUMV neurosurgery operating rooms. The patients included will be adults 18 years old or older, who will be scheduled for surgery by the Neurosurgery service. Those who meet the selection criteria determined for this study will be chosen consecutively and will be followed from the immediate preoperative moment until 72 hours after the end of the surgery. Data collection shall be carried out by direct observation and immersion in clinical records of patients who have signed the informed consent. The study will be carried out in 4 phases: immediate preoperative, intraoperative, immediate postoperative and late postoperative, recording the data using various measuring instruments, and a record sheet. Finally, the cumulative incidence of LPPs developed in the perioperative environment will be calculated and a statistical analysis will be performed.

Participants needed: 170
Trial details
Age: 18-100Biological sex: AllType: ObservationalSponsor: Instituto de Investigación Marqués de ValdecillaUpdated: Sep 26, 2024Locations: 2
Eligibility criteria

Patients who understand and sign the informed consent. [+4]

Patients who do not sign informed consent. [+8]