Health Trials

Previously Treated Amyloid Light-chain (AL) Amyloidosis

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Review clinical trials related to Previously Treated Amyloid Light-chain (AL) Amyloidosis. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

A Study of JNJ-79635322 in Participants With Relapsed or Refractory Multiple Myeloma or Previously Treated Amyloid Light-chain (AL) Amyloidosis

The primary purpose of this study is to identify the recommended phase 2 dose (RP2D\[s\]) and schedule(s) to be safe for JNJ-79635322 in Part 1 (dose escalation), and to characterize the safety and tolerability of JNJ-79635322 at the RP2D(s) selected and in disease subgroups in Part 2 (dose expansion).

Participants needed: 180
Trial details
Phase: Phase 1Age: 18+Biological sex: AllType: InterventionalSponsor: Janssen Research & Development, LLCUpdated: Jun 5, 2026Locations: 29
Eligibility criteria

Have a documented initial diagnosis of multiple myeloma according to Internation... [+8]

Central Nervous System (CNS) involvement or clinical signs of meningeal involvem... [+20]

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