Primary Motor Cortex

2

Review clinical trials related to Primary Motor Cortex. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

rTMS Induced Reduction in M1 Excitability

When learning a new skill, much of the improvement comes from small alterations the brain makes with each repetition during practice, but this isn't the only time that improvements are made during the learning process. Individuals also get better at the motor skills during the time between practices, through a process called "consolidation." It is known that an area of the brain called the primary motor cortex is involved in learning during active practice, but the investigators want to study if the primary motor cortex is important for consolidation. The investigators will examine how lowering the activity in this brain region affects your ability to consolidate learning to play a song on the videogame Guitar Hero.

Participants needed: 32
Trial details
Age: 18-45Biological sex: AllType: InterventionalSponsor: Indiana UniversityUpdated: Jun 1, 2026Locations: 1
Eligibility criteria

Between ages 18 and 45 years old (to avoid any changes in the developing brain,... [+3]

Currently prescribed and taking stimulant medication (Adderall, Ritalin, Vyvanse... [+3]

Status: Recruiting

Prophylactic Anti-Seizure Medication vs No Anti-Seizure Medication for Patients With Primary Motor Cortex Brain Metastases

This is a randomized trial for patients with brain metastases in the primary motor cortex who have not had seizures to receive either the prophylactic anti-seizure medication levetiracetam (also known by its trade name Keppra) or proceed with standard of care management, which does not currently include prophylactic levetiracetam. Patients who enroll to this trial will be randomized to receive prophylactic levetiracetam or not receive prophylactic levetiracetam.

Participants needed: 150
Trial details
Phase: Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: Ayal A. Aizer, MDUpdated: Mar 19, 2026Locations: 1
Eligibility criteria

Participants must have a biopsy proven solid malignancy with at least one intrac... [+4]

Participants with prior seizures as this is a study for seizure naïve patients [+8]