Progressive Multifocal Leucoencephalopathy (PML)

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Review clinical trials related to Progressive Multifocal Leucoencephalopathy (PML). Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

T-cell Therapy in Patients With PML

There is no approved standard treatment für progressive multifocal leukoencephalopathy (PML). The sponsor of the study is developing a new treatment. For this reason, the investigational medicinal product (IMP) called 'human allogenic HPyV-2-specific T cells' is to be tested in this study. The sponsor wants to find out whether the IMP is safe, influences the neurological status and improves the quality of the life of patients . It is to be investigated whether the IMP can be used to treat the disease and whether it could have an advantage over the standard therapy in terms of survival rate.

Participants needed: 23
Trial details
Phase: Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: Hannover Medical SchoolUpdated: Feb 12, 2026Locations: 6
Eligibility criteria

Adults* aged ≥ 18 years with PML (diagnosed ≤ 60 days before screening) associat... [+2]

PML caused by HIV [+10]