Prostate Disease

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Review clinical trials related to Prostate Disease. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

5-Alpha Reductase 2 as a Marker of Resistance to 5ARI Therapy

The study is being conducted to learn why some patients with Benign Prostatic Hyperplasia (BPH) do not respond to a commonly used treatment drug, Finasteride. The hope is to find ways to predict which patients will not respond to Finasteride so that, in the future, these patients can be identified prior to offering this treatment and they can be offered alternative treatment strategies in its place. The aim is to see if noninvasive techniques such as MRI can detect inflammation of the prostate to assist with early detection of those who will and who will not respond to Finasteride.

Participants needed: 120
Trial details
Age: 50+Biological sex: MaleType: InterventionalSponsor: Beth Israel Deaconess Medical CenterUpdated: Oct 28, 2025Locations: 1
Eligibility criteria

Male (physiological); [+7]

Diagnosis of any prostatic malignancy or precancerous lesions (atypical glandula... [+6]

Status: Recruiting

Exploring the Potential of Robotic Telesurgery in Remote Settings

This study involves a type of robotic surgery called telesurgery, where a highly trained surgeon performs the surgical procedure using a secure internet connection to operate on a patient in a different location. Urologists from The goal of this study is to find out how safe and effective telesurgery is when used in real hospitals. The study aims to understand how well Telesurgery works in different settings, what technical challenges might come up (like internet speed or delays), and how it can be used to train new surgeons.

Participants needed: 10
Trial details
Age: 18-90Biological sex: MaleType: InterventionalSponsor: AdventHealthUpdated: Aug 19, 2025Locations: 1
Eligibility criteria

Age 18 - 90 [+5]

Uncontrolled cardiovascular, pulmonary, or metabolic disease. [+6]

Status: Recruiting

Evaluation of the Performance of a Novel Prostate Biopsy System Compared With Standard of Care Biopsy Needle on Quantitative and Qualitative Tissue Parameters

Currently used biopsy devices do not predictably obtain full cores of tissue and the tissue obtained is often fragmented and disrupted making it difficult for pathological review. This post-market study will assess the utility of the SUREcore biopsy needle and the coreCARE specimen retrieval device versus a standard of care biopsy needle and the typical tissue container used in urology offices and clinics today.

Participants needed: 200
Trial details
Age: 18-90Biological sex: MaleType: InterventionalSponsor: Uro-1 MedicalUpdated: May 7, 2025Locations: 1
Eligibility criteria

Adult male scheduled for prostate biopsy [+2]

Unwilling to provide consent

Status: Recruiting

TURP Inpatient With Underactive Bladder With BOO

The study is for aproved that Transurtheral Resection of prostate is good for patient with underactive bladder or not.

Participants needed: 50
Trial details
Age: 40-70Biological sex: MaleType: InterventionalSponsor: Sohag UniversityUpdated: Apr 25, 2025Locations: 1
Eligibility criteria

Male patients diagnosed with BOO and UAB [+1]

Patient insulin dependent diabetes [+5]

Status: Recruiting

High Resolution Diffusion Weighted Imaging in Prostate

hrDWI might be an alternative to cDWI for the prostate imaging. 1. increase the signal-to-noise ratio and contrast-to-noise ratio, yielding high-fidelity images with less noise in general 2. improve the diagnostic accuracy of PCa in particular than conventional DWI

Participants needed: 500
Trial details
Age: 55+Biological sex: MaleType: ObservationalSponsor: The First Affiliated Hospital with Nanjing Medical UniversityUpdated: Oct 15, 2024Locations: 2
Eligibility criteria

Patients who underwent standard MR scanning including T2WI, cDWI , hrDWI and res... [+1]