Health Trials

Protein Kinase Inhibitors

2

Review clinical trials related to Protein Kinase Inhibitors. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Single vs. Dual Antiplatelet Therapy in Elderly or HBR Patients Undergoing Percutaneous Intervention With DCB (PICCOLETO IV-EPIC 38)

This international, multicenter, open-label, randomized clinical trial evaluates the safety and efficacy of single antiplatelet therapy (SAPT) compared to dual antiplatelet therapy (DAPT) in elderly or high bleeding risk patients undergoing percutaneous coronary intervention (PCI) with the latest generation drug-coated balloon (DCB). The study includes patients with stable or unstable coronary syndromes and aims to assess rates of ischemic and bleeding adverse events.

Participants needed: 576
Trial details
Biological sex: AllType: InterventionalSponsor: Fondazione Ricerca e Innovazione Cardiovascolare ETSUpdated: Jan 22, 2026Locations: 1
Eligibility criteria

Age ≥ 75 years or age ≥ 18 years at high bleeding risk; [+4]

Stent implantation during index or recent (<6 months) procedure; [+24]

Read more
Status: Recruiting

Phase I Study of JYP0322 in ROS1 Fusion-Positive Solid Tumors

An open, non-randomized, multicenter, single-arm dose-escalation design, phase 1 trial to study the safety, tolerability, pharmacokinetics and efficacy of JYP0322 in patients with ROS1+ locally advanced/metastatic solid tumors .

Participants needed: 101
Trial details
Phase: Phase 1Age: 18+Biological sex: AllType: InterventionalSponsor: Guangzhou JOYO Pharma Co., LtdUpdated: Jul 14, 2025Locations: 1
Eligibility criteria

Adult patients age 18 years or older. [+4]

Current participation in another therapeutic clinical trial. [+4]

Read more