Psychedelic Microdosing Effects on Mood, Cognition, Subjective Well-being and MRI

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Review clinical trials related to Psychedelic Microdosing Effects on Mood, Cognition, Subjective Well-being and MRI. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Psilocybin Microdosing on Cognition, Mood and Quality of Life

This study is being conducted to evaluate how of 30 days of intermittently microdosed psilocybin affects mood, cognition, subjective well-being and structural/functional MRI results compared to a placebo. Investigators hypothesize that compared to placebo, 30 days of intermittently microdosed psilocybin will produce observable changes in mood, cognition, subjective well-being and MRI, in the absence of psychedelic experiences.

Participants needed: 20
Trial details
Phase: Early Phase 1Age: 21-40Biological sex: AllType: InterventionalSponsor: Yale UniversityUpdated: Jun 23, 2026Locations: 1
Eligibility criteria

No history of psychedelic use [+3]

Positive screen for recreational drugs or alcohol on test day will result in res... [+10]