Psychological Flexibility

6

Review clinical trials related to Psychological Flexibility. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Comparative Effects of Four Brief Breathwork and Mindfulness Interventions on Anxiety and Psychological Flexibility: A 4-Arm RCT

This four-arm, single-blind randomized controlled trial examines the effects of four brief daily 5-minute practices over 28 days on psychological flexibility and physiological variables in Spanish-speaking adults. Participants will be randomly assigned to one of four groups: Box Breathing, Cyclic Sighing, Mindfulness focused on exhalation with the syllable "AH", or Conscious Cyclic Sighing. Outcomes include state and trait anxiety (STAI), positive and negative affect (PANAS), psychological flexibility (MPFI-24, Psy-Flex), and physiological variables (heart rate, respiratory rate, heart rate variability). Assessments are conducted at baseline, daily during the 28-day intervention, at post-intervention (day 31), and at 2-month follow-up.

Participants needed: 240
Trial details
Age: 18-65Biological sex: AllType: InterventionalSponsor: Valencian International University (VIU)Updated: Jun 4, 2026
Eligibility criteria

Age between 18 and 65 years (inclusive) [+3]

Active diagnosis of severe or chronic respiratory disease that prevents safe per... [+2]

Status: Not yet recruiting

Positive Psychology Based Psychoeducation for Psychological Flexibility and Perceived Stress in University Students

This study will test whether an 8-week multi-component positive psychology-based psychoeducation program can reduce perceived stress and improve psychological flexibility among first-year undergraduate nursing students. Eligible students who provide informed consent will be randomly assigned to either an intervention group or a waitlist control group. The intervention group will attend weekly 60-75 minute psychoeducation sessions including brief psychoeducation, experiential exercises, shared reflection, and home practice assignments. The waitlist control group will continue their usual routine during the study period and will not receive any intervention before post-test assessment. Outcomes will be assessed at baseline and immediately after the 8-week program using the Perceived Stress Scale-14 and the Acceptance and Action Questionnaire-II.

Participants needed: 66
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Harran UniversityUpdated: May 12, 2026
Eligibility criteria

Being a first-year undergraduate student in the Department of Nursing at Harran... [+3]

Receiving regular psychotherapy or psychoeducation during the same academic peri... [+2]

Status: Not yet recruiting

ACT-Based Group Therapy and Mobile Application Intervention for Emotional Eating

This study aims to evaluate the effects of an Acceptance and Commitment Therapy (ACT)-based group therapy program, combined with an ACT-based mobile app, on emotional eating, emotion regulation, and psychological flexibility in overweight individuals. Emotional eating is a condition in which individuals frequently use eating behavior as a coping mechanism for negative emotions. Participants will be randomly assigned to intervention groups receiving ACT-based group therapy, ACT-based group therapy combined with an ACT-based mobile app, or a control group. The intervention will last six weeks and will include structured group sessions as well as mobile-based exercises, reminders, and coping strategies. Outcome measures will include emotional eating, emotion regulation, and psychological flexibility. Assessments will be conducted at baseline, post-intervention, and during the follow-up phase. The findings of this study are expected to contribute to the development of accessible and effective interventions for emotional eating.

Participants needed: 78
Trial details
Age: 18-65Biological sex: AllType: InterventionalSponsor: Saglik Bilimleri UniversitesiUpdated: Apr 30, 2026Locations: 1
Eligibility criteria

Agreeing to participate in the study, [+6]

Having communication problems that would prevent the interview, [+5]

Status: Recruiting

ACT With CF Self-Help Toolkit

Acceptance and Commitment Therapy (ACT) tailored to meet the needs of adults living with cystic fibrosis (ACT with CF) is a newer form of talk therapy that has been shown to reduce anxiety \& depression and improve psychological flexibility, and value-based living. The investigators are now trying to find out whether a self-help version of this treatment (ACT with CF - Self Help Toolkit) is also effective in reducing anxiety and depression and improving psychological flexibility and value-based living in adults with CF. Adults with cystic fibrosis are at increased risk for anxiety and depression. This study examines whether a patient-facing therapy, ACT with CF - Self Help Toolkit can help to reduce anxiety and depression among adults with CF. This treatment can be accessed on the participant's smartphone.

Participants needed: 60
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Thomas Jefferson UniversityUpdated: Mar 3, 2026Locations: 1
Eligibility criteria

18 years or older [+2]

History of suicide attempts or acute suicidal ideation on clinical assessment [+3]

Status: Recruiting

A Pilot Study on an ACT-Based Program for Individuals With Special Needs and Their Caregivers

Parenting children with special health care needs can be stressful and weigh on the caregivers' mental health. For the individuals with special needs, the mismatch between their needs and the normative practice in the world around them can be frustrating and detrimental to their functioning. The demands and concerns to these families can be so real that it may not be sensible to examine the validity or helpfulness of the distressing thoughts or feelings but to promote psychological flexibility, which is a key to value-guided living. This pilot study explores the effects and feasibility of a group-based intervention for families of individuals with special health care needs.

Participants needed: 62
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: The University of Hong KongUpdated: Jan 16, 2026Locations: 1
Eligibility criteria

be at or older than 18 years old [+2]

with borderline or greater intellectual deficits [+2]

Status: Recruiting

Acceptance and Commitment Therapy-based Intervention for Parents of a Child With Medical Complexity

A pilot randomized controlled trial of an Acceptance and Commitment Therapy-based intervention will be conducted to decrease psychological symptoms, while increase psychological flexibility for parents of a child with medical complexity during their difficulties.

Participants needed: 30
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: The Hong Kong Polytechnic UniversityUpdated: Jul 8, 2025Locations: 2
Eligibility criteria

parent of a child with medical complexity aged 1-18 [+2]

a reported mental health disorder [+2]