Ptosis, Eyelid

2

Review clinical trials related to Ptosis, Eyelid. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Comparative Study of Ziplyft Treatment vs. Traditional Blepharoplasty for Upper Eyelid Rejuvenation

This study will compare two surgery techniques used for upper eyelid (eyelift) surgery: traditional surgery and a newer method called Ziplyft (a non-powered, hand-held clamp). This study will use a "split-face" design, meaning one eyelid will be treated with the traditional surgery method and the other with Ziplyft, allowing a direct side-by-side comparison. The objectives of the study are to compare Ziplyft treatment vs. traditional surgery by evaluating bruising, wound closure and incision, surgery case time, and subject/surgeon surveys.

Participants needed: 50
Trial details
Age: 35+Biological sex: AllType: InterventionalSponsor: Osheru Inc.Updated: Nov 26, 2025Locations: 1
Eligibility criteria

Provide signed written consent prior to participation in any study-related proce... [+4]

Subjects with a current Ptosis diagnosis [+9]

Status: Recruiting

Anterior Versus Posterior White Line Advancement Technique in the Correction of Aponeurotic Ptosis

The goal of this clinical trial is to compare the efficacy of two surgical techniques-anterior and posterior white line advancement-for the correction of primary aponeurotic ptosis in adult patients. The main questions it aims to answer are: Does the anterior approach lead to a greater improvement in Marginal Reflex Distance 1 (MRD1) at 6 months compared to the posterior approach? Are there differences in eyelid symmetry, contour, visual function, and patient satisfaction between the two techniques? Researchers will compare the anterior approach group to the posterior approach group to see if one offers better functional and aesthetic outcomes, fewer complications, or higher patient satisfaction. Participants will: Be randomly assigned to receive either anterior or posterior white line advancement surgery. Undergo preoperative and postoperative evaluations at 7 days, 2 months, and 6 months, including: Measurements of eyelid position (MRD1), contour, and symmetry Vision and tear film tests (e.g., refraction, TBUT, Schirmer's test) Surveys on dry eye symptoms (OSDI), scar quality (POSAS 2.0), satisfaction, and psychosocial function Monitoring of surgical time and complications

Participants needed: 54
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Instituto de Investigación Sanitaria de la Fundación Jiménez DíazUpdated: Oct 7, 2025Locations: 1
Eligibility criteria

Age over 18 years. [+3]

Diagnosis of non-aponeurotic eyelid ptosis. [+5]