Pulmonary Hypoplasia

4

Review clinical trials related to Pulmonary Hypoplasia. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia (FETO)

The purpose of this research is to gather information on the safety and effectiveness of a new procedure called Fetoscopic Endoluminal Tracheal Occlusion (FETO).

Participants needed: 10
Trial details
Age: 18-50Biological sex: FemaleType: InterventionalSponsor: Rodrigo RuanoUpdated: Feb 23, 2026Locations: 2
Eligibility criteria

Singleton pregnancy [+5]

Multi-fetal pregnancy [+12]

Status: Recruiting

Safety and Efficacy of FETO in CDH Phase III

Tracheal occlusion IDE approved by FDA for congenital diaphragmatic hernia fetuses and standard of care control group

Participants needed: 75
Trial details
Phase: Phase 3Age: 18-50Biological sex: FemaleType: InterventionalSponsor: Children's Hospital Medical Center, CincinnatiUpdated: Sep 22, 2025Locations: 1
Eligibility criteria

Pregnant women 18 years and older, who are able to consent [+9]

Patient < 18 years of age [+16]

Status: Recruiting

Safety and Efficacy of FETO in CDH: A Phase III Trial

Congenital diaphragmatic hernia (CDH) is a birth defect characterized by the development of a hole in the diaphragm, the breathing muscle that separates the chest from the abdomen. As a result, organs in the abdomen can move into the chest and press on the developing lungs. This prevents the lungs from growing and developing normally. In severe cases, CDH can lead to serious disease and death at birth. For these babies, treatment before birth may allow the lungs to grow enough before birth so these children are capable of surviving and thriving.

Participants needed: 80
Trial details
Age: 18+Biological sex: FemaleType: InterventionalSponsor: Holly L Hedrick, MDUpdated: Jul 25, 2025Locations: 2
Eligibility criteria

Pregnant women age 18 years and older [+8]

Patient is less than 18 years of age [+16]