Pulpotomy

8

Review clinical trials related to Pulpotomy. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

R. Officinalis as Pulpotomy Agent in Permanent Teeth With Irreversible Pulpitis

This study evaluates and compares the clinical and radiographic outcomes of Rosmarinus officinalis and Mineral Trioxide Aggregate (MTA) when used as pulpotomy medicaments in vital mature permanent teeth with irreversible pulpitis. The aim is to determine the effectiveness of both materials in terms of pain reduction and periapical healing. While MTA is considered a gold standard, it has limitations such as high cost, long setting time, and potential discoloration. Therefore, this study investigates Rosmarinus officinalis as a natural, cost-effective alternative with comparable therapeutic potential. This study also provide an alternative to RCT in teeth with irreversible pulpitis

Participants needed: 100
Trial details
Age: 18-40Biological sex: AllType: InterventionalSponsor: University of Health Sciences LahoreUpdated: May 27, 2026Locations: 1
Eligibility criteria

Healthy patients (ASA classification 1 and 2) of age range of 18-40 of both sexe... [+6]

Patients with ASA classification 3, 4 ,5 and 6 would be [+4]

Status: Recruiting

Clinical and Radiographic Success of MTA vs Biodentine

The purpose of this prospective study is to compare the clinical and radiographic success of MTA and Biodentine as a medicament in vital pulp therapy in maxillary and mandibular primary molars in a pediatric population. There is limited research currently on Biodentine since it's a novel product. Biodentine is less expensive than MTA and does not cause discoloration like MTA. Biodentine may be an alternative medicament used for vital pulp therapy in primary molars.

Participants needed: 646
Trial details
Phase: Phase 4Age: 2-12Biological sex: AllType: InterventionalSponsor: Geisinger ClinicUpdated: Dec 23, 2025Locations: 1
Eligibility criteria

Male or female patients ages of 2 to ≤12 years. [+4]

Pre-operative radiographic or clinical symptoms associated with irreversible pul... [+4]

Status: Recruiting

Comparison of Clinical Success of Stainless Steel Crowns and Zirconia Crowns in Primary Molars

Evaluation and understanding of clinical success, parental satisfaction and effects on periodontal tissues are the main expected benefits of prefabricated zirconia crowns and prefabricated stainless steel crowns. For a long time, stainless steel crowns have been the restorative material of choice for children's primary and permanent posterior teeth. Today, prefabricated zirconia crowns are more popular than other options because they meet aesthetic expectations and have high mechanical strength. The aim of this study is to evaluate and compare the periodontal health, plaque accumulation, opposing tooth wear, parental satisfaction, and clinical performance (color match, retention, marginal integrity, marginal discoloration, anatomic form, secondary caries, surface roughness, surface gloss and postoperative sensitivity) of pediatric prefabricated stainless steel and zirconia crowns applied after pulpotomy to asymptomatic, multifaceted, deep carious primary mandibular second molars.

Participants needed: 10
Trial details
Age: 4-5Biological sex: AllType: InterventionalSponsor: Aydin Adnan Menderes UniversityUpdated: Dec 22, 2025Locations: 1
Eligibility criteria

Age range of children from 4 to 5 years. [+9]

Having a systemic disease. [+6]

Status: Not yet recruiting

Clinical and Radiographic Evaluation of Potassium Nitrate in Polycarboxylate Versus Mineral Trioxide Aggregate in Vital Pulpotomy in Primary Molars

The purpose of this RCT is to compare the clinical/radiographic outcomes of Potassium nitrate in polycarboxylate cement and MTA as pulpotomy biomaterials used for asymptomatic vital primary lower second molar and this will help to clinically evaluate the use of alternative material in vital pulpotomy in primary molars with deep carious cavities. Emphasis is set on avoiding total pupectomy and maintaining radicular pulp vitality therefore maintain the tooth in a viable condition till it's shedding and eruption of the permanent successor.

Participants needed: 50
Trial details
Age: 4-7Biological sex: AllType: InterventionalSponsor: Cairo UniversityUpdated: Mar 12, 2025Locations: 1
Eligibility criteria

Children aged 4 to 7 years, in good general health. [+6]

Children with a physical disability or medical disability. [+5]

Status: Not yet recruiting

Clinical and Radiographic Evaluation of Chitosan Versus Formocresol After Vital Pulpotomy of Primary Molars

The goal of this clinical trial is to evaluate whether Chitosan liquid will show similar clinical and radiographical success rate compared to Formocresol when used in vital pulp therapy in primary molars. The main question it aims to answer is: * Will Chitosan liquid, in comparison to Formocresol, show similar clinical outcomes in relation to presence/absence of post-operative pain, swelling, sinus and/or fistula formation when used in vital pulpotomy in primary molars? * Will Chitosan liquid, in comparison to Formocresol, show similar radiographical outcomes in relation to presence/absence of furcal involvement, periapical lesion, pathological root resorption and/or widening of periodontal membrane space when used in vital pulpotomy in primary molars? Following conventional pulpotomy procedure, the primary investigator will evaluate the effect of placing a cotton pellet damp with Chitosan liquid directly on radicular vital pulp compared to that of placing a cotton pellet damp with Formocresol on radicular vital pulp. Primary teeth included in both arms of the study will be restored by zinc oxide and eugenol and covered by a stainless steel crown as final restoration. The clinical trail will be followed up for 1 year. Clinical outcomes will be evaluated every 3 months. Radiographic outcomes will be evaluated every 6 months.

Participants needed: 50
Trial details
Age: 4-8Biological sex: AllType: InterventionalSponsor: Cairo UniversityUpdated: Feb 5, 2025Locations: 1
Eligibility criteria

Healthy cooperative children with at least one deep carious mandibular primary m... [+4]

Excessive haemorrhage that cannot be stopped by a damp cotton pellet after sever... [+4]

Status: Recruiting

Clinical and Radiographic Evaluation of Vital Pulpotomy Techniques in Primary Molars Using of Premixed Bioactive Bioceramic MTA (Neo-putty) as a Novel Pulpotomy Medication Versus Formocresol

Despite the benefit of formocresol, there are toxic effects allergic reactions and local soft and hard tissue necrosis have been reported when such formaldehyde compounds were used clinically, however, the adverse effect of the clinically used of this compound are not widely reported. It has been stated that it has a side effect on the permanent successor although it results as a successful technique for the treatment of the primary teeth

Participants needed: 44
Trial details
Age: 4-9Biological sex: AllType: InterventionalSponsor: October University for Modern Sciences and ArtsUpdated: Dec 20, 2024Locations: 1
Eligibility criteria

4 -9 years old [+3]

Patients with systemic diseases (congenital or rheumatic heart disease, hepatiti... [+2]

Status: Recruiting

Assessment of I-PRF Versus Nano MTA Combined with I-PRF Scaffold in Vital Pulp Therapy in Mature Mandibular First Molars

Assessment of I-PRF versus Nano Mineral trioxide aggregate Combined with I-PRF in pulpotomy in mature Mandibular First Molars

Participants needed: 51
Trial details
Age: 15-30Biological sex: AllType: InterventionalSponsor: Future University in EgyptUpdated: Oct 15, 2024Locations: 1
Eligibility criteria

Patients suffering from Symptomatic irreversible pulpitis in mature mandibular m... [+8]

Patients with immature roots. [+5]

Status: Not yet recruiting

Clinical and Radiographic Evaluation of Bioceramic Putty MTA Versus MTA in Pulpotomy of Immature Permanent Molars

The present study aims to evaluate the clinical and radiographic success of bioceramics putty MTA versus MTA in the pulpotomy of immature permanent molars The main question it aims to answer is: Will the biocermaics putty MTA have higher clinical and radiographic success rates than MTA in pulpotomy of immature permanent molars?

Participants needed: 40
Trial details
Phase: Phase 3Age: 6-8Biological sex: AllType: InterventionalSponsor: Cairo UniversityUpdated: Jul 23, 2024Locations: 1
Eligibility criteria

Patients aged from 6-8 years of both sexes have immature permanent molars [+5]

Medically compromised patients who have systemic disease. [+2]