Status: Recruiting
Characterization and Contribution of Genome-wide DNA Methylation (DNA Methylation Episignatures) in Rare Diseases With Prenatal Onset
It is necessary to define reference DNA Methylation Episignatures from fetal DNA. The hypotheses are: * It is possible to define reference DNA Methylation Episignatures from fetal DNA extracted from amniotic fluid or frozen tissues collected during the postmortem examination * Fetal DNA Methylation Episignatures may be different to postanal DNA Methylation Episignatures defined on DNA extracted from blood
Participants needed: 63
Trial details
Age: 0-18Biological sex: AllType: ObservationalSponsor: Assistance Publique - Hôpitaux de ParisUpdated: Mar 27, 2026Locations: 1
Eligibility criteria
Fetuses with a postmortem examination as part of the etiological diagnosis of de... [+9]
Refusal of postmortem examination in case of fetal loss [+1]