RB1 Gene Mutation

1

Review clinical trials related to RB1 Gene Mutation. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Safety/Efficacy Study of CID-078 in Patients With Advanced Solid Tumor Malignancies

This is a first-in-human, multicenter, open-label, phase 1 study to evaluate safety, tolerability, and efficacy of CID-078, a Cyclin A/B-RxL inhibitor, in patients with advanced solid tumors.

Participants needed: 220
Trial details
Phase: Phase 1Age: 12+Biological sex: AllType: InterventionalSponsor: Circle PharmaUpdated: Sep 15, 2025Locations: 10
Eligibility criteria

Part 1a Dose Escalation and Part 1b New Formulation Dose Escalation/Pilot Food E... [+17]

Targeted therapy ≤ eight days or 5× the terminal phase elimination half-lives, w... [+76]