Reconstructive Surgery

4

Review clinical trials related to Reconstructive Surgery. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

App-Assisted Swallowing Program After Oral Cancer Surgery

This study aims to examine the effects of a swallowing care program combined with an exercise mobile application (App) on swallowing function, anxiety, and quality of life in patients with oral cancer after flap reconstruction surgery. The goal is to determine whether integrating App-based swallowing exercises into postoperative care can improve rehabilitation outcomes compared with conventional care alone. A purposive sampling method will be used to recruit 72 participants from the surgical wards of a medical center in northern Taiwan. Eligible patients scheduled for oral cancer tumor resection and flap reconstruction will be identified through consultation with plastic surgeons. After screening and informed consent, participants will be assigned to a control group or an experimental group, with approximately 36 patients in each group. The control group will receive routine ward education and standard postoperative nursing care, while the experimental group will receive the same care plus an additional intervention using a swallowing exercise App. The intervention will begin on postoperative day 7, guided by the researcher. Follow-up assessments will be conducted during outpatient visits at postoperative week 4 and week 12. To minimize potential interference between participants, data collection will be performed sequentially-first for the control group, followed by the experimental group. Data will be collected through self-administered questionnaires or researcher-assisted interviews, including a demographic survey, the Postoperative Oral Dysfunction-10 (POD-10), the Functional Oral Intake Scale (FOIS), a Visual Analog Scale for Anxiety, and the EORTC QLQ-H\&N35 questionnaire for quality of life. Each assessment will take approximately 20-30 minutes. Participants may withdraw from the study at any time without penalty. Descriptive statistics will be used to summarize participant characteristics. The chi-square test and independent t-test will be used to examine group homogeneity. Paired t-tests will be applied to evaluate within-group changes in swallowing function, anxiety, and quality of life before and after the intervention. The results of this study are expected to provide empirical evidence on the effectiveness of App-assisted swallowing rehabilitation for patients with oral cancer following reconstructive surgery, supporting the development of innovative, technology-based postoperative care models.

Participants needed: 72
Trial details
Age: 18+Biological sex: AllType: InterventionalSponsor: Chang Gung Memorial HospitalUpdated: Dec 24, 2025Locations: 1
Eligibility criteria

Willing to sign a written informed consent form [+5]

Diagnosed by a physician with poor postoperative wound healing that prevents par... [+1]

Status: Recruiting

Postoperative Management of Patients Undergoing Head and Neck Microvascular Free Flap Reconstructive Surgery: is Admission to an Intensive Care Unit Necessary?

The aim of our study is to assess if patients undergoing head and neck free flap reconstructive surgery admitted to the ICU have equivalent postoperative outcomes to those admitted to an Otolaryngology specialty ward

Participants needed: 192
Trial details
Biological sex: AllType: ObservationalSponsor: Fondazione IRCCS Policlinico San Matteo di PaviaUpdated: Dec 19, 2025Locations: 1
Eligibility criteria

patients undergoing Head and Neck oncological demolitive surgery and reconstruct...

patients treated for Head and Neck cancer without flap reconstruction (e.g., onl...

Status: Recruiting

The Association Between Radiation Dermatitis and Skin Microbiome in Breast Cancer Patients

The breast cancer patients who received radiotherapy after mastectomy and breast reconstruction will be enrolled. The skin microbiome before radiotherapy and its changes after radiotherapy will be analyzed systematically to find out whether the skin microbiome is associated with the severity of radiation dermatitis.

Participants needed: 100
Trial details
Age: 18-70Biological sex: FemaleType: ObservationalSponsor: Fudan UniversityUpdated: Sep 2, 2021Locations: 1
Eligibility criteria

Female patients [+5]

Previous breast or chest radiotherapy [+3]

Status: Recruiting

AFT: Introduction of a Full Breast Reconstructive Method

A multicentre prospective cohort study will monitor the efficacy and safety of Autologous Fat Transfer (AFT) with pre-expansion. AFT will be evaluated in terms of quality of life, aesthetic result, complications, oncological safety and cost-effectiveness. It follows the BREAST trial, the randomised controlled trial comparing AFT with implant-based reconstruction. In this study, patients all receive AFT.

Participants needed: 350
Trial details
Age: 18+Biological sex: FemaleType: ObservationalSponsor: Maastricht University Medical CenterUpdated: Jul 29, 2021Locations: 8
Eligibility criteria

Female gender [+6]

Active smoker or a history of smoking 4 weeks prior to surgery [+14]