Rectus Sheath Closure

1

Review clinical trials related to Rectus Sheath Closure. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

Comparing Polyglactin vs Polypropylene Sutures for Rectus Sheath Closure

This randomized controlled trial aims to compare the outcomes of Polyglactin (Vicryl) versus Polypropylene (Prolene) sutures for rectus sheath closure in patients undergoing midline laparotomy. The study will evaluate the rates of incisional hernia, surgical site infection (SSI), wound dehiscence, chronic pain, and suture sinus formation. Participants aged 18-70 years, undergoing either elective or emergency laparotomy, will be randomly assigned to receive either Polyglactin or Polypropylene sutures. The primary outcome measure is the incidence of incisional hernia at 6 months, with secondary outcomes including SSI, wound complications, and chronic pain. The study is particularly important in the context of Pakistan, where such comparative data is limited, and aims to provide evidence-based recommendations for optimal suture material selection in general surgery.

Participants needed: 156
Trial details
Age: 18-70Biological sex: AllType: InterventionalSponsor: Lady Reading Hospital, PakistanUpdated: Dec 15, 2025Locations: 1
Eligibility criteria

Age: 18-70 years. [+4]

Contaminated or Dirty Wounds: Patients with CDC Class III or IV wounds. [+6]