Health Trials

Recurrent and/or Metastatic Head and Neck Squamous Cell Carcinoma

1

Review clinical trials related to Recurrent and/or Metastatic Head and Neck Squamous Cell Carcinoma. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Study to Evaluate the Safety and Efficacy of Oral NRC-2694-A in Combination With Paclitaxel in Patients With Recurrent and/or Metastatic Head and Neck Squamous Cell Carcinoma, Who Progressed on or After Immune Checkpoint Inhibitor Therapy

This is a Phase 2, open-label, multicenter, single-arm study of NRC-2694-A in combination with paclitaxel in patients with R/M HNSCC with progression on or after ICI therapy. A total of approximately 46 male and female patients will be enrolled. This sample size is based on Simon's 2-stage design with historical control ORR of 30% and a target ORR of 50%.

Participants needed: 21
Trial details
Phase: Phase 2Age: 18+Biological sex: AllType: InterventionalSponsor: NATCO Pharma Ltd.Updated: Jan 23, 2026Locations: 13
Eligibility criteria

Is willing and capable of understanding the written informed consent, provides s... [+10]

Has cardiac, hepatic, endocrine, pulmonary, or autoimmune disease, interstitial... [+19]

Read more