Recurrent Nasopharynx Carcinoma

2

Review clinical trials related to Recurrent Nasopharynx Carcinoma. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

EGFR Antibody Combined With PD-1 Inhibitor and Chemotherapy in R/M Nasopharyngeal Carcinoma

This is a prospective, single-arm, phase II clinical trial. The purpose of this study is to evaluate the efficacy and adverse effect of EGFR antibody combined with programmed death 1 (PD-1) antibody and chemotherapy in recurrent/metastatic nasopharyngeal carcinoma patients.

Participants needed: 148
Trial details
Phase: Phase 1, Phase 2Age: 18-75Biological sex: AllType: InterventionalSponsor: Sun Yat-sen UniversityUpdated: May 11, 2026Locations: 1
Eligibility criteria

Patients with nasopharyngeal carcinoma who have recurred/metastasized after init... [+12]

Patients with recurrence who can be treated with local resection or radiotherapy... [+12]

Status: Recruiting

PD-1 Inhibitor Plus Chemotherapy Followed by Immediate Versus Selective Re-irradiation for Locally Advanced Recurrent NPC

This phase II randomized trial evaluates PD-1 inhibitor plus chemotherapy followed by immediate versus selective re-irradiation in locally advanced recurrent nasopharyngeal carcinoma. The study aims to determine whether sequential radiotherapy provides additional survival benefit beyond systemic immunochemotherapy.

Participants needed: 94
Trial details
Phase: Phase 2Age: 18-70Biological sex: AllType: InterventionalSponsor: Sun Yat-sen UniversityUpdated: Feb 4, 2026Locations: 1
Eligibility criteria

Age 18-70 years, any gender. [+8]

Presence of grade 3 or higher late radiation toxicity (excluding skin, subcutane... [+14]