Recurrent or Metastatic Breast Cancer

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Review clinical trials related to Recurrent or Metastatic Breast Cancer. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Not yet recruiting

A Phase III Study of SYS6010 Versus Chemotherapy in HER2-Negative, EGFR-Positive Recurrent or Metastatic Breast Cancer

This study is a multicenter, randomized, open-label, parallel-control Phase III clinical trial enrolling patients with unresectable HER2-negative, EGFR-positive recurrent/metastatic breast cancer who have previously failed first- or second-line chemotherapy. It aims to compare the efficacy and safety of SYS6010 monotherapy versus investigator-selected chemotherapy.The study plans to enroll approximately 400 subjects, randomly assigned in a 1:1 ratio to the treatment arm and control arm(Investigator's choice of standard chemotherapy regimen, including eribulin, capecitabine, gemcitabine, or vinorelbine).

Participants needed: 400
Trial details
Phase: Phase 3Age: 18-75Biological sex: AllType: InterventionalSponsor: CSPC Megalith Biopharmaceutical Co.,Ltd.Updated: Feb 12, 2026
Eligibility criteria

Age 18 to 75 years inclusive, no gender restrictions. [+8]

Presence of cancerous meningitis, spinal cord compression, or active central ner... [+7]