Health Trials

Red Blood Cell Disorder

2

Review clinical trials related to Red Blood Cell Disorder. Use filters to narrow results by trial status, phase, treatment, biological sex and sponsor.

Condition / disease
Location
Status: Recruiting

Nonmyeloablative Stem Cell Transplant in Children With Sickle Cell Disease and a Major ABO-Incompatible Matched Sibling Donor

The aim of this study to evaluate the safety and efficacy of a nonmyeloablative conditioning regimen for allogeneic hematopoietic stem cell transplantation (HSCT) in pediatric patients with sickle cell disease (SCD) who have a matched related major ABO-incompatible donor. The nonmyeloablative regimen will use alemtuzumab, total body irradiation (TBI) and sirolimus for immune suppression. This study will expand the access of HSCT for patients with SCD who are currently not eligible because of donor restrictions.

Participants needed: 12
Trial details
Phase: Phase 2Age: 1-19Biological sex: AllType: InterventionalSponsor: University of CalgaryUpdated: May 1, 2026Locations: 1
Eligibility criteria

Patients must be ≥ 12 months and < 19 years of age at the time of study enrollme... [+13]

Patients who are unable to comply with or follow the study protocol. [+1]

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Status: Recruiting

Pathophysiological Explorations of Red Blood Cells

GR-Ex is a program labelled by Labex (Laboratory of Excellence) by the French Ministry of Higher Education and Research. This program aims to develop the means to improve knowledge in the physiology and pathologies of erythropoiesis, red blood cells and iron metabolism, and to develop new therapeutic protocols capable of providing added value in terms of innovation.

Participants needed: 3,750
Trial details
Biological sex: AllType: ObservationalSponsor: Imagine InstituteUpdated: Apr 30, 2025Locations: 25
Eligibility criteria

To be affected or have a family history of disease bound to the red blood cell, [+3]

Being deprived of freedom

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